Fluorenyl Moxycarbonyl Succinimide
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names fluorenyl moxycarbonyl succinimide
Structure
CAS No. 82911-69-1 Boiling Point (℃) 494.3±38.0 °C at 760 mmHg
Molecular Weight 337.326 Melting Point (℃) 150-153 °C(lit.)
Density 1.4±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C19H15NO5 Flash Point (℃) 252.7±26.8 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description DL-Lysine (Lysine) is an α-amino acid that is used in the biosynthesis of proteins.
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.
Synonyms
MFCD00010733
2,5-Pyrrolidinedione, 1-(((9H-fluoren-9-ylmethoxy)carbonyl)oxy)-
1-{[(9H-fluoren-9-ylmethoxy)carbonyl]oxy}pyrrolidine-2,5-dione
9-Fluorenylmethyl succinimidyl carbonate
N-(9-Fluorenylmethoxycarbonyloxy) succinimide
1-{[(9H-Fluoren-9-ylmethoxy)carbonyl]oxy}pyrrolidin-2,5-dion
2,5-dioxotetrahydro-1H-pyrrol-1-yl (9H-fluoren-9-ylmethyl) carbonate
1-{[(9H-Fluoren-9-ylmethoxy)carbonyl]oxy}-2,5-pyrrolidinedione
(2,5-dioxopyrrolidin-1-yl) 9H-fluoren-9-ylmethyl carbonate
EINECS 433-520-5
2,5-Pyrrolidinedione, 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-
Fmoc-OSu
Product Description
Fluorenylmoxycarbonyl succinimide (FMOC-Succinimide) is an amino acid derivative that belongs to the family of FMOC-protected amino acids. It is widely used in the synthesis of peptides and proteins in the pharmaceutical industry.

FMOC-Succinimide is produced through the reaction of succinimide with FMOC-Cl in the presence of a base such as triethylamine. The resulting product is a white powder that is soluble in organic solvents such as DMF, DMSO, and CHCl3.

One of the main advantages of using FMOC-Succinimide as a protective group is its stability to a wide range of reaction conditions. This allows for the synthesis of peptides and proteins under harsh reaction conditions without the risk of deprotection or cleavage of the FMOC group. Additionally, FMOC-Succinimide can be easily removed using mild base treatment, which does not affect the peptide or protein backbone.

The market for FMOC-Succinimide is expected to grow in the coming years, driven by the increasing demand for peptides and proteins in the pharmaceutical industry. The rise in demand for peptide therapeutics, which have the potential to treat a wide range of diseases, is expected to be a key driver of growth. Additionally, the increasing use of peptides in drug discovery and development is expected to drive demand for FMOC-Succinimide.

In terms of regional market trends, North America and Europe are currently the largest markets for FMOC-Succinimide, owing to the presence of major pharmaceutical companies and research institutions in these regions. However, the Asia-Pacific region is expected to see the highest growth rate, driven by the growing pharmaceutical industry in countries such as China and India.

In conclusion, FMOC-Succinimide is a widely used amino acid derivative that has proven to be a valuable protective group in the synthesis of peptides and proteins. With the increasing demand for peptide therapeutics and the growing pharmaceutical industry in Asia-Pacific, the market for FMOC-Succinimide is expected to continue to grow in the coming years.

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