BOC-anhydride
DBDC
EINECS 246-240-1
Carbonic acid, (1,1-dimethylethoxy)carbonyl 1,1-dimethylethyl ester
Boc2O
DIBOC,BOC
Dibutyldicarbonate
Di-tert-butyl dicarbonate
Pyrocarbonic Acid Di-tert-butyl Ester
Di-tert-butyl Pyrocarbonate
Di-tert-butyldicarbonat
Di-tert-Butyldicarbonate
di(tert-butyl) carbonate
Di(tert-butyl) dicarbonate

Di-tert-butyl dicarbonate (Boc anhydride) is a commonly used amino acid protecting reagent in the field of peptide synthesis. It is a colorless liquid with a pungent odor, and has the chemical formula C10H18O5. The compound is highly reactive and is used to block the amine group of amino acids, protecting it from unwanted side reactions during peptide synthesis.

Production and Application: Di-tert-butyl dicarbonate is produced through the reaction of isobutene with phosgene. It is a highly flammable and toxic substance, and requires careful handling during production and usage. The compound is widely used in the synthesis of peptides and proteins, as well as in the preparation of drugs and pesticides.

In peptide synthesis, Di-tert-butyl dicarbonate is commonly used as a protecting reagent for the amine group of amino acids. It reacts with the amine group, forming a Boc-protected amino acid, which can be further used in the synthesis of longer peptide chains. The Boc protecting group can be easily removed by treatment with acid, revealing the unmodified amine group for further reactions.

Market Industry Development: The global market for Di-tert-butyl dicarbonate is expected to grow steadily in the coming years. The growing demand for peptide-based drugs and the increasing use of Di-tert-butyl dicarbonate in the pharmaceutical industry are key drivers of market growth. Additionally, the compound's versatility and easy handling make it an attractive option for use in peptide synthesis.

In conclusion, Di-tert-butyl dicarbonate is an important amino acid protecting reagent that plays a crucial role in peptide synthesis and drug development. Despite its toxicity and potential hazards, the compound's importance in the pharmaceutical industry ensures continued demand and growth in the global market.