β-Alanine
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names β-alanine
Structure
CAS No. 107-95-9 Boiling Point (℃) 237.1±23.0 °C at 760 mmHg
Molecular Weight 89.093 Melting Point (℃) 202 °C (dec.)(lit.)
Density 1.2±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C3H7NO2 Flash Point (℃) 97.2±22.6 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
Target Human Endogenous Metabolite
In Vitro Cells treated with β-alanine display significantly suppressed basal and peak ECAR (aerobic glycolysis), with simultaneous increase in glucose transporter 1 (GLUT1). Additionally, cells treated with β-alanine exhibit significantly reduced basal and peak OCR (oxidative metabolism), which is accompanied by reduction in mitochondrial content with subsequent suppression of genes which promote mitochondrial biosynthesis. Suppression of glycolytic and oxidative metabolism by β-alanine results in the reduction of total metabolic rate, although cell viability is not affected.β-alanine is shown to reduce both cell migration and proliferation without acting in a cytotoxic fashion. Moreover, β-alanine significantly increases malignant cell sensitivity to doxorubicin, suggesting a potential role as a co-therapeutic agent[1].
References [1]. Vaughan RA, et al. β-alanine suppresses malignant breast epithelial cell aggressiveness through alterations in metabolism and cellular acidity in vitro. Mol Cancer. 2014 Jan 24;13:14.
Synonyms
3-Aminopropanoic acid
beta-alanine
3-Aminopropionic Acid
EINECS 203-536-5
MFCD00008200
β-Alanine
H-β-Ala-OH
Product Description
β-alanine is a non-essential amino acid that has gained increasing attention as a food ingredient due to its potential performance-enhancing benefits. As a building block of carnosine, a dipeptide found in high concentrations in skeletal muscle tissue, β-alanine has been shown to increase muscle carnosine levels, which may delay muscle fatigue and improve exercise performance.
As a food ingredient, β-alanine is commonly used in sports nutrition products, such as pre-workout supplements and protein powders, as well as functional foods and beverages. It is generally recognized as safe (GRAS) by the US Food and Drug Administration (FDA) and has been approved for use in foods and supplements in many other countries.
In addition to its potential performance-enhancing benefits, β-alanine has been suggested to have antioxidant and anti-inflammatory properties, which may contribute to its overall health-promoting effects. However, more research is needed to fully understand the potential benefits and safety of long-term β-alanine supplementation.
When used as a food ingredient, β-alanine is typically added in the form of a powder, which can be easily incorporated into a variety of food and beverage formulations. It has a slightly sweet, neutral taste and is generally well-tolerated at recommended dosages.
Overall, β-alanine is a versatile food ingredient that offers potential benefits for athletes and active individuals. As with any dietary supplement, it is important to follow recommended dosages and to consult with a healthcare professional before use, especially if you have any underlying health conditions.
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