N-trityl glycine methyl ester
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names n-tritylglycine methyl ester
Structure
CAS No. 10065-71-1 Boiling Point (℃) N/A
Molecular Weight 331.408 Melting Point (℃) N/A
Density N/A Vapor Specific Gravity N/A
Molecular Formula C22H21NO2 Flash Point (℃) N/A
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description DL-Lysine (Lysine) is an α-amino acid that is used in the biosynthesis of proteins.
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.
Synonyms
Glycine,N-trityl-,methyl ester (8CI)
methyl N-tritylglycinate
N-Tritylglycine methyl ester
glycine,N-(triphenylmethyl)-,methyl ester
N-Trityl-glycin-methylester
GLYCINE,N-TRITYL,METHYL ESTER
Product Description
Introduction: N-Trityl Glycine Methyl Ester is a chemical compound widely used in the field of organic synthesis. It serves as a versatile building block and intermediate in various chemical reactions. This product finds applications in the pharmaceutical, chemical, and research industries due to its unique properties and potential uses.

Raw Materials: N-Trityl Glycine Methyl Ester is synthesized using high-quality raw materials, including trityl chloride and glycine methyl ester. Trityl chloride, also known as trityl chloride resin, is derived from trityl alcohol and serves as a protecting group in organic synthesis. Glycine methyl ester is obtained through appropriate chemical reactions and subsequent purification steps, ensuring the desired quality of the final product.

Production Process: The production of N-Trityl Glycine Methyl Ester involves a series of carefully controlled steps to ensure consistent product quality. Trityl chloride is first reacted with glycine methyl ester under specific conditions, forming a stable ester bond. The reaction mixture undergoes purification techniques such as filtration, crystallization, and drying, resulting in a white or off-white crystalline powder as the final product.

Market Trends: N-Trityl Glycine Methyl Ester has gained significant attention in the pharmaceutical and chemical industries due to its potential applications. In the pharmaceutical sector, it is widely used as a protecting group for amino acids and peptides during the synthesis of pharmaceutical compounds. In the chemical industry, it serves as a valuable intermediate for the synthesis of various organic compounds and functional materials. The market demand for N-Trityl Glycine Methyl Ester is driven by the need for efficient and reliable methods for protecting and manipulating functional groups in organic synthesis.

Amino Acid Status: N-Trityl Glycine Methyl Ester plays a crucial role in amino acid and peptide chemistry. It acts as a protecting group, shielding the amino group of glycine from unwanted reactions during chemical transformations. This protective function allows for selective modifications and controlled synthesis of peptides and amino acid derivatives. By facilitating the manipulation of amino acids, N-Trityl Glycine Methyl Ester contributes to the advancement of research and the development of new pharmaceutical compounds.

Conclusion: N-Trityl Glycine Methyl Ester is a valuable chemical compound with diverse applications in the pharmaceutical and chemical industries. Its synthesis from high-quality raw materials and stringent production processes ensure consistent product quality. The market demand for this product is expected to continue growing due to its unique properties and potential applications in organic synthesis, particularly in the protection and modification of amino acids and peptides. With its various applications and contributions to organic chemistry, N-Trityl Glycine Methyl Ester offers a valuable tool for researchers and chemists, enabling the development of novel compounds and advancements in the field of pharmaceuticals and materials science.

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