N-acetyl-L-tryptophan
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names Acetyl-L-tryptophan
Structure
CAS No. 1218-34-4 Boiling Point (℃) 586.6±45.0 °C at 760 mmHg
Molecular Weight 246.262 Melting Point (℃) 190ºC
Density 1.3±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C13H14N2O3 Flash Point (℃) 308.6±28.7 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description N-Acetyl-L-tryptophan is an endogenous metabolite.
Target Human Endogenous Metabolite
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.
Synonyms
L-Tryptophan, N-acetyl-
N-Acetyl-L-tryptophan
EINECS 214-935-9
(2S)-2-acetamido-3-(1H-indol-3-yl)propanoic acid
N-Acetyltryptophan
MFCD00065976
Acetyl-L-tryptophan
(S)-N-Acetyltryptophan
Tryptophan, N-acetyl-, L-
(S)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid
N-Acetyl-Trp-OH
Ac-Trp-OH
Product Description
Introduction: N-Acetyl-L-Tryptophan is a chemical compound derived from L-tryptophan, an essential amino acid known for its important role in protein synthesis and neurotransmitter regulation. N-Acetyl-L-Tryptophan is widely used in the pharmaceutical, dietary supplement, and research industries due to its potential health benefits and various applications.

Raw Materials: N-Acetyl-L-Tryptophan is synthesized using high-quality raw materials, primarily L-tryptophan and acetic anhydride. L-tryptophan, obtained through enzymatic or chemical processes, serves as the starting material for the synthesis. Acetic anhydride, a common reagent, is used for acetylation to produce N-Acetyl-L-Tryptophan.

Production Process: The production of N-Acetyl-L-Tryptophan involves precise control of reaction conditions to ensure the desired product quality. L-tryptophan is first obtained from a reliable source and then reacted with acetic anhydride under specific conditions. The acetylation reaction is carefully monitored, and the resulting N-Acetyl-L-Tryptophan is purified using techniques such as crystallization and filtration to obtain a pure and stable form.

Market Trends: N-Acetyl-L-Tryptophan has gained significant attention in the pharmaceutical and dietary supplement industries due to its potential health benefits. It is known to support serotonin synthesis, which plays a crucial role in mood regulation and sleep quality. The market demand for N-Acetyl-L-Tryptophan is driven by the growing consumer interest in natural and nutritional products that promote overall well-being and mental health.

Amino Acid Status: L-tryptophan is an essential amino acid that cannot be synthesized by the body and must be obtained through dietary sources. It serves as a precursor for various important molecules, including serotonin and melatonin. N-Acetyl-L-Tryptophan, derived from L-tryptophan through acetylation, offers enhanced stability and bioavailability, making it a valuable compound for nutritional and pharmaceutical applications.

Conclusion: N-Acetyl-L-Tryptophan is a valuable compound with potential health benefits and applications in the pharmaceutical and dietary supplement industries. Its synthesis from high-quality raw materials and strict production processes ensures consistent product quality. The market demand for N-Acetyl-L-Tryptophan is expected to continue growing, driven by consumer interest in natural and nutritional products that support mental well-being. With its potential contributions to serotonin synthesis and overall health, N-Acetyl-L-Tryptophan provides a valuable option for formulation and application in various industries, supporting mental health, sleep quality, and overall wellness.

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