N-acetyl-L-lysine
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names N6-trifluoroacetyl-L-lysine
Structure
CAS No. 10009-20-8 Boiling Point (℃) 382.5±42.0 °C at 760 mmHg
Molecular Weight 242.196 Melting Point (℃) 258ºC
Density 1.3±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C8H13F3N2O3 Flash Point (℃) 185.1±27.9 °C
Solubility 2 M HCl: 10 mg/mL, clear, colorless Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description H-Lys(Tfa)-OH is a lysine derivative[1].
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
Synonyms
L-Lysine, N6-(2,2,2-trifluoroacetyl)-
H-Lys(Tfa)-OH
(S)-2-Amino-6-pivalamidohexanoic acid
N6-(Triflu​oroacetyl)​-L-lysine
N-(Trifluoroacetyl)-L-lysine
Nepsilon-Trifluoroacetyl-L-lysine
Nepsilon-(Trifluoroacetyl)-L-lysine
N(6)-trifluoroacetyl-L-lysine
MFCD00037223
L-Lysine, N-(2,2,2-trifluoroacetyl)-
(2S)-2-amino-6-[(2,2,2-trifluoroacetyl)amino]hexanoic acid
QVYZ4MVXFFF &&L or S Form
Ne-Trifluoroacetyl-L-lysine
Product Description
Introduction: N-Acetyl-L-lysine, commonly known as N-Acetyllysine or NAL, is a significant chemical compound with diverse applications in the chemical industry. This product introduction aims to provide an overview of N-Acetyl-L-lysine, covering its raw materials, production process, market trends, and the current status of amino acids in the industry.

Raw Materials: N-Acetyl-L-lysine is synthesized using L-lysine and acetic anhydride as the primary raw materials. L-lysine, an essential amino acid, serves as the precursor for NAL synthesis. Acetic anhydride provides the acetyl group necessary for acetylation.

Production Process: The production process of N-Acetyl-L-lysine involves the following steps:
Step 1: Esterification reaction - L-lysine is reacted with acetic anhydride in the presence of suitable catalysts and reaction conditions to form N-Acetyl-L-lysine. The reaction takes place in a solvent or under solid-state conditions, depending on the specific manufacturing process.

Step 2: Purification and refinement - The resulting N-Acetyl-L-lysine is purified and refined using techniques such as filtration, crystallization, and chromatography to achieve the desired level of purity.

Market Trends: The market demand for N-Acetyl-L-lysine has been steadily increasing due to its diverse applications across various industries. Here are some key market trends:
Pharmaceuticals: N-Acetyl-L-lysine is utilized in the pharmaceutical industry. It is used as an ingredient in the formulation of drugs targeting liver health, detoxification, and metabolic support. It also finds applications in the development of amino acid-based supplements.

Cosmetics and Personal Care: N-Acetyl-L-lysine finds applications in cosmetics and personal care products. It is used in skincare formulations due to its potential to promote skin hydration, improve skin barrier function, and support the synthesis of collagen and elastin.

Chemical Research: N-Acetyl-L-lysine serves as a valuable compound in chemical research. It is utilized as a building block in the synthesis of peptides, pharmaceutical intermediates, and specialty chemicals. Its unique structure and functional groups make it useful for diverse synthetic applications.

Current Status of Amino Acids: Amino acids play a crucial role in various sectors, including pharmaceuticals, food additives, animal nutrition, and agriculture. The demand for amino acids continues to grow due to their diverse applications and essential role in biological processes. Essential amino acids, such as L-lysine, are of particular importance as they cannot be synthesized by the human body and must be obtained through diet or supplementation.

Conclusion: N-Acetyl-L-lysine, derived from L-lysine, holds significant value in the chemical industry. Its production involves the combination of raw materials and precise manufacturing processes. The market demand for N-Acetyl-L-lysine is driven by its applications in pharmaceuticals, cosmetics, personal care, and chemical research. Amino acids, including L-lysine, continue to play a vital role in various industries, and N-Acetyl-L-lysine maintains its position as a valuable chemical compound with diverse applications.