N-acetyl-L-glutamine
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names Aceglutamide
Structure
CAS No. 2490-97-3 Boiling Point (℃) 419.0±55.0 °C at 760 mmHg
Molecular Weight 188.181 Melting Point (℃) 206-208 °C
Density 1.4±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C7H12N2O4 Flash Point (℃) 207.2±31.5 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description Aceglutamide is a psychostimulant and nootropic, used to improve memory and concentration.
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.
Synonyms
N-ACETYL GLUTAMINE
ACETYL-L-GLUTAMINE,N
L-N2-acetyl-Glutamine
L-Norvaline, 5-hydroxy-N-(1-hydroxyethylidene)-5-imino-, (Z)-
MFCD00038159
N-Acetyl-L-GlutaMine Acid
ACETYL-L-GLUTAMINE
N-α-acetyl-L-glutamine
L-Glutamine, N-acetyl-
Glutamine, N2-acetyl-, L-
N-Acetyl-L-glutamine
a-N-Acetyl-L-glutamine
Glutamine, N-acetyl-
Product Description
Introduction: N-Acetyl-L-Glutamine is a chemical compound derived from L-glutamine, an essential amino acid. It is widely used in the pharmaceutical, dietary supplement, and personal care industries due to its various health benefits and versatile applications. N-Acetyl-L-Glutamine is known for its role in supporting gut health, immune function, and overall well-being.

Raw Materials: N-Acetyl-L-Glutamine is synthesized using high-quality raw materials, primarily L-glutamine and acetic anhydride. L-glutamine is obtained through fermentation or chemical processes from natural sources. Acetic anhydride, a commonly used reagent, is employed for acetylation to produce N-Acetyl-L-Glutamine.

Production Process: The production of N-Acetyl-L-Glutamine involves careful control of reaction conditions to ensure the desired product quality. L-glutamine serves as the starting material and undergoes acetylation with acetic anhydride under specific reaction conditions. The acetylation reaction is closely monitored, and the resulting N-Acetyl-L-Glutamine is purified using techniques such as crystallization and filtration to obtain a pure and stable form.

Market Trends: N-Acetyl-L-Glutamine has gained significant popularity in the pharmaceutical and dietary supplement industries due to its potential benefits for gut health and immune function. The market demand for N-Acetyl-L-Glutamine is driven by the increasing consumer interest in digestive health and immune support. People are seeking natural and effective solutions to maintain a healthy gut microbiome and enhance their immune system, leading to the growing demand for N-Acetyl-L-Glutamine.

Amino Acid Status: L-glutamine is a conditionally essential amino acid that plays a crucial role in various physiological processes, including protein synthesis, immune function, and gut health. N-Acetyl-L-Glutamine, derived from L-glutamine through acetylation, offers improved stability and bioavailability, making it a valuable compound for various applications. Its ability to support gut health and enhance immune function makes it an attractive ingredient in the formulation of dietary supplements and functional foods.

Conclusion: N-Acetyl-L-Glutamine is a valuable compound with potential health benefits and applications in the pharmaceutical and dietary supplement industries. Its synthesis from high-quality raw materials and strict production processes ensures consistent product quality. The market demand for N-Acetyl-L-Glutamine is expected to continue growing, driven by the increasing consumer focus on gut health and immune function. With its potential contributions to digestive health and immune support, N-Acetyl-L-Glutamine provides a valuable option for formulation and application in various industries, promoting overall well-being and a healthy lifestyle.

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