Synonyms
Ac-D-Leu-OH
D-Leucine, N-acetyl-
Leucine, N-acetyl-, DL-
Ac-DL-Leu-OH
Leucine, N-acetyl-
2-acetamido-4-methylpentanoic acid
DL-Leucine, N-acetyl-
(R)-N-acetyl-leucine
Ac-Leu-OH
N-Acetylleucine
(R)-2-Acetamido-4-methylpentanoic acid
UNII:K76S41V71X
EINECS 202-734-9
MFCD00026498
N-acetyl-leucine
(2R)-2-acetamido-4-methylpentanoic acid
Acetylleucine
Product Description
Introduction:
N-Acetyl-DL-leucine, commonly known as N-Acetylleucine or NAL, is a significant chemical compound with
diverse applications in the chemical industry. This product introduction aims to provide an overview of
N-Acetyl-DL-leucine, covering its raw materials, production process, market trends, and the current
status of amino acids in the industry.
Raw Materials:
N-Acetyl-DL-leucine is synthesized using DL-leucine and acetic anhydride as the primary raw materials.
DL-leucine, an essential amino acid, serves as the precursor for NAL synthesis. Acetic anhydride
provides the acetyl group necessary for acetylation.
Production Process:
The production process of N-Acetyl-DL-leucine involves the following steps:
Step 1: Esterification reaction - DL-leucine is reacted with acetic anhydride in the presence of
suitable catalysts and reaction conditions to form N-Acetyl-DL-leucine. The reaction takes place in a
solvent or under solid-state conditions, depending on the specific manufacturing process.
Step 2: Purification and refinement - The resulting N-Acetyl-DL-leucine is purified and refined using
techniques such as filtration, crystallization, and chromatography to achieve the desired level of
purity.
Market Trends:
The market demand for N-Acetyl-DL-leucine has been steadily increasing due to its diverse applications
across various industries. Here are some key market trends:
Pharmaceuticals: N-Acetyl-DL-leucine is widely used in the pharmaceutical industry. It is utilized as an
active pharmaceutical ingredient (API) in the formulation of drugs targeting neurological disorders,
cognitive health, and nervous system support.
Sports and Performance Nutrition: N-Acetyl-DL-leucine finds applications in the sports and performance
nutrition sector. It is included in pre-workout and intra-workout supplements to enhance athletic
performance, muscle recovery, and endurance.
Chemical Research: N-Acetyl-DL-leucine serves as a valuable compound in chemical research. It is used as
a building block in the synthesis of peptides, pharmaceutical intermediates, and specialty chemicals.
Its unique structure and functional groups make it useful for diverse synthetic applications.
Current Status of Amino Acids:
Amino acids play a crucial role in various sectors, including pharmaceuticals, food additives, animal
nutrition, and agriculture. The demand for amino acids continues to grow due to their diverse
applications and essential role in biological processes. Essential amino acids, such as DL-leucine, are
of particular importance as they cannot be synthesized by the human body and must be obtained through
diet or supplementation.
Conclusion:
N-Acetyl-DL-leucine, derived from DL-leucine, holds significant value in the chemical industry. Its
production involves the combination of raw materials and precise manufacturing processes. The market
demand for N-Acetyl-DL-leucine is driven by its applications in pharmaceuticals, sports nutrition, and
chemical research. Amino acids, including DL-leucine, continue to play a vital role in various
industries, and N-Acetyl-DL-leucine maintains its position as a valuable chemical compound with diverse
applications.