N-acetyl-D-leucine
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names (2R)-2-acetamido-4-methylpentanoic acid
Structure
CAS No. 19764-30-8 Boiling Point (℃) 369.6±25.0 °C at 760 mmHg
Molecular Weight 173.21 Melting Point (℃) 176-177ºC
Density 1.1±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C8H15NO3 Flash Point (℃) 177.4±23.2 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description N-Acetyl-R-leucine is an amino protecting group N-substituted chiral amino acid[1].
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Wang MZ, et al. Synthesis method of amino protecting group N-substituted chiral amino acid. CN114195684.
Synonyms
MFCD00066069
Ac-D-Leu-OH
D-leucine,N-acetyl
D-Leucine, N-acetyl-
N-Ac-D-leucine
2,N-Acetyl-D-leucine
N-Acetyl-D-leucine
(R)-N-acetyl-leucine
(R)-2-Acetamido-4-methylpentanoic acid
N-acetylleucin
N-Acetyl-D-leucin
(2R)-2-acetamido-4-methylpentanoic acid
N-Acethy-D-leucine
Product Description
Introduction: N-Acetyl-D-Leucine is a chemical compound derived from D-leucine, a naturally occurring amino acid. It is widely used in the pharmaceutical, dietary supplement, and research industries due to its potential health benefits and versatile applications. N-Acetyl-D-Leucine is known for its role in supporting brain health, neurological function, and overall well-being.

Raw Materials: N-Acetyl-D-Leucine is synthesized using high-quality raw materials, primarily D-leucine and acetic anhydride. D-leucine is obtained through fermentation or chemical processes from natural sources. Acetic anhydride, a commonly used reagent, is employed for acetylation to produce N-Acetyl-D-Leucine.

Production Process: The production of N-Acetyl-D-Leucine involves careful control of reaction conditions to ensure the desired product quality. D-leucine serves as the starting material and undergoes acetylation with acetic anhydride under specific reaction conditions. The acetylation reaction is closely monitored, and the resulting N-Acetyl-D-Leucine is purified using techniques such as crystallization and filtration to obtain a pure and stable form.

Market Trends: N-Acetyl-D-Leucine has gained significant attention in the pharmaceutical industry and among researchers due to its potential benefits for neurological health and cognitive function. The market demand for N-Acetyl-D-Leucine is driven by the growing interest in brain health supplements and the increasing awareness of the importance of maintaining optimal neurological function. Consumers are seeking natural and effective solutions to support cognitive well-being, leading to the rise in demand for N-Acetyl-D-Leucine.

Amino Acid Status: D-leucine is an essential amino acid that plays a vital role in protein synthesis, muscle development, and overall health. N-Acetyl-D-Leucine, derived from D-leucine through acetylation, offers improved stability and bioavailability, making it a valuable compound for various applications. Its ability to cross the blood-brain barrier enhances its potential in supporting neurological function and cognitive health.

Conclusion: N-Acetyl-D-Leucine is a valuable compound with potential health benefits and applications in the pharmaceutical and dietary supplement industries. Its synthesis from high-quality raw materials and strict production processes ensures consistent product quality. The market demand for N-Acetyl-D-Leucine is expected to continue growing, driven by the increasing interest in brain health and cognitive function. With its potential contributions to neurological health and overall well-being, N-Acetyl-D-Leucine provides a valuable option for formulation and application in various industries, supporting cognitive function and promoting a healthy lifestyle.

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