N-Acetyl-L-tyrosine ethyl ester monohydrate
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names Ethyl N-acetyl-L-tyrosinate hydrate (1:1)
Structure
CAS No. 36546-50-6 Boiling Point (℃) 464.4±35.0 °C at 760 mmHg
Molecular Weight 251.278 Melting Point (℃) 80-81 °C(lit.)
Density 1.2±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C13H17NO4 Flash Point (℃) 234.6±25.9 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description Ac-Tyr-OEt.H2O is a tyrosine derivative[1].
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
Synonyms
ATEE MONOHYDRATE
N-Acetyl-L-tyrosine ethyl ester hydrate
ACETYL-L-TYROSINE ETHYL ESTER HYDRATE
N-ACETYL TYROSINE ETHYL ESTER HYDRATE
Ac-Tyr-OEt.H2O
Ethyl N-acetyl-L-tyrosinate hydrate (1:1)
N-Acetyl-L-Tyr-OEt
L-Tyrosine, N-acetyl-, ethyl ester
N-ACETYLTYROSINE ETHYL ESTER 1-HYDRATE
N-Acetyl-L-tyrosine ethylester monohydrate
Product Description
Introduction: N-Acetyl-L-tyrosine ethyl ester monohydrate, commonly known as N-Acetyltyrosine ethyl ester or NALT, is a significant chemical compound with diverse applications in the chemical industry. This product introduction aims to provide an overview of N-Acetyl-L-tyrosine ethyl ester monohydrate, covering its raw materials, production process, market trends, and the current status of amino acids in the industry.

Raw Materials: N-Acetyl-L-tyrosine ethyl ester monohydrate is synthesized using L-tyrosine, acetic anhydride, and ethanol as primary raw materials. L-tyrosine, a non-essential amino acid, serves as the precursor for NALT synthesis. Acetic anhydride provides the acetyl group necessary for acetylation, while ethanol acts as a solvent and reaction medium.

Production Process: The production process of N-Acetyl-L-tyrosine ethyl ester monohydrate involves the following steps:
Step 1: Esterification reaction - L-tyrosine is reacted with acetic anhydride in the presence of suitable catalysts and reaction conditions to form N-Acetyl-L-tyrosine ethyl ester. The reaction takes place in an ethanol solvent, facilitating the esterification process.

Step 2: Monohydrate formation - The N-Acetyl-L-tyrosine ethyl ester is further processed to obtain the monohydrate form, typically through crystallization or precipitation in the presence of water.

Step 3: Purification and refinement - The resulting N-Acetyl-L-tyrosine ethyl ester monohydrate is purified and refined using techniques such as filtration, drying, and crystallization to achieve the desired level of purity.

Market Trends: The market demand for N-Acetyl-L-tyrosine ethyl ester monohydrate has been steadily increasing due to its diverse applications across various industries. Here are some key market trends:
Nutraceuticals and Dietary Supplements: N-Acetyl-L-tyrosine ethyl ester monohydrate is widely used in the production of nutraceuticals and dietary supplements. Its inclusion in these products is driven by its potential to support cognitive function, mood enhancement, and stress reduction.

Sports Nutrition: The compound is utilized in sports nutrition formulations due to its role in supporting athletic performance, focus, and mental clarity.

Pharmaceutical Industry: N-Acetyl-L-tyrosine ethyl ester monohydrate finds applications in the pharmaceutical industry. It is used as a precursor in the synthesis of various drugs and therapeutic compounds targeting neurological disorders, mood regulation, and cognitive health.

Current Status of Amino Acids: Amino acids play a crucial role in various sectors, including pharmaceuticals, food additives, animal nutrition, and agriculture. The demand for amino acids continues to grow due to their diverse applications and essential role in biological processes. Both essential and non-essential amino acids are widely utilized in the industry.

Conclusion: N-Acetyl-L-tyrosine ethyl ester monohydrate, derived from L-tyrosine, holds significant value in the chemical industry. Its production involves the combination of raw materials and precise manufacturing processes.