L-Proline methyl ester hydrochloride
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names H-Pro-OMe.HCl
Structure
CAS No. 2133-40-6 Boiling Point (℃) 169.9ºC at 760 mmHg
Molecular Weight 165.618 Melting Point (℃) 69-71ºC
Density 1.055g/cm3 Vapor Specific Gravity N/A
Molecular Formula C6H12ClNO2 Flash Point (℃) 56.5ºC
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description DL-Lysine (Lysine) is an α-amino acid that is used in the biosynthesis of proteins.
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.
Synonyms
Methyl (2S)-2-pyrrolidinecarboxylate hydrochloride
H-L-PRO-OME HCL
L-Proline Methyl Ester HCl
Proline,Methyl ester,HCl
(S)-2-carbomethoxypyrrolidine hydrochloride
L-Proline methyl est
H-Pro-OMe·HCl
L-Prolinemethylesterhydrochloride
Methyl L-prolinate hydrochloride (1:1)
methyl (S)-2-pyrrolidinecarboxylate hydrochloride
H-Pro-OMe.HCl
Methyl Proline Hydrochloride
(S)-proline methyl ester hydrochloride
EINECS 218-363-0
proline methyl ester hydrochloride
Product Description
L-Proline Methyl Ester Hydrochloride is a specialized compound that holds significant importance in various industries due to its unique properties and wide range of applications. Derived from L-proline, an essential amino acid, this product offers numerous benefits in pharmaceutical, research, and chemical sectors. With its high purity and versatility, L-proline methyl ester hydrochloride is a valuable ingredient in many applications.

Production: L-Proline Methyl Ester Hydrochloride is produced through a controlled synthesis process, starting from L-proline. The esterification of L-proline with methanol under precise conditions leads to the formation of high-quality L-proline methyl ester hydrochloride. The production process ensures the purity, stability, and consistency of the final product, meeting strict quality standards and industry regulations.

Applications: Pharmaceutical Industry: L-Proline Methyl Ester Hydrochloride finds extensive use in the pharmaceutical industry for drug synthesis and research purposes. It serves as a key intermediate in the production of various pharmaceutical compounds, including peptide-based drugs, neuroprotective agents, and immunosuppressants. Its unique chemical structure and properties make it valuable for drug development and formulation.

Peptide Synthesis: L-Proline Methyl Ester Hydrochloride is widely employed in peptide synthesis, particularly for the incorporation of proline residues in peptide chains. Proline is known for its role in stabilizing peptide structures, and the use of L-proline methyl ester hydrochloride facilitates the efficient synthesis of proline-containing peptides. It enables the creation of peptides with specific conformations and functional properties.

Chemical Synthesis: L-Proline Methyl Ester Hydrochloride serves as a versatile building block in chemical synthesis processes. It is utilized in the production of various organic compounds, such as pharmaceutical intermediates, natural product synthesis, and chiral catalysts. Its unique chemical reactivity and compatibility make it a valuable tool for chemists and synthetic laboratories.

Market Outlook: The market outlook for L-Proline Methyl Ester Hydrochloride is promising, driven by the increasing demand from the pharmaceutical and chemical industries. The pharmaceutical sector's constant need for new drug compounds and the growing focus on peptide-based therapies contribute to the rising demand for L-proline methyl ester hydrochloride.

Additionally, the expanding scope of peptide synthesis and chemical synthesis methods fuels the market growth for L-proline methyl ester hydrochloride. As industries strive for innovative solutions and advanced synthetic techniques, L-proline methyl ester hydrochloride offers unique opportunities for the development of novel compounds and pharmaceutical intermediates.

Furthermore, the compound's potential applications in other industries, such as cosmetics and food additives, provide additional market prospects. As the demand for functional ingredients and bioactive compounds increases, L-proline methyl ester hydrochloride can find utilization in these sectors as well.

In conclusion, L-Proline Methyl Ester Hydrochloride is a valuable compound with diverse applications in pharmaceuticals, peptide synthesis, and chemical synthesis. Its production process ensures high purity and quality, meeting the stringent requirements of various industries. With the increasing demand for peptide-based therapies, novel drug compounds, and advanced synthetic methods, the market for L-proline methyl ester hydrochloride is expected to witness significant growth in the coming years.

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