L-Homoproline
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names L-Homoproline
Structure
CAS No. 3105-95-1 Boiling Point (℃) 265.8±33.0 °C at 760 mmHg
Molecular Weight 129.157 Melting Point (℃) 272ºC
Density 1.1±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C6H11NO2 Flash Point (℃) 114.5±25.4 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description H-HoPro-OH is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as Zellweger syndrome, neonatal adrenoleukodystrophy.
Target Human Endogenous Metabolite
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Mihalik SJ, et al. Peroxisomal L-pipecolic acid oxidation is deficient in liver from Zellweger syndrome patients. Pediatr Res. 1989 May;25(5):548-52.
Synonyms
(S)-piperidine-2-carboxylic acid
PIP-OH
L-PIPECOLATE
H-HOMOPRO-OH
(2S)-piperidine-2-carboxylic acid
(S)-2-Piperidinecarboxylic acid
Pipecolinic acid
6-CARBOXYPIPERIDINE
DL-2-Piperidinecarboxylic acid
Pipecolic acid
α-Pipecolinic acid
a-Pipecolinic acid
HOMOPROLINE
L-HOMOPRO
L-Homoproline
Product Description
L-homoproline, also known as 4-hydroxy-L-proline, is an amino acid that plays a crucial role in the formation of collagen in the human body. It is derived from proline, which is converted into hydroxyproline through a series of enzymatic reactions. As a chemical and pharmaceutical intermediate, L-homoproline has various applications in the synthesis of drugs, including antivirals, antibiotics, and anticancer agents.

From a medical standpoint, L-homoproline has potential therapeutic benefits as an anti-inflammatory agent and antioxidant. It can also aid in wound healing, bone regeneration, and skin rejuvenation. As a result, there is a growing demand for L-homoproline in the pharmaceutical industry, with an increasing number of clinical trials exploring its therapeutic potential.

The production of L-homoproline involves a series of steps, including fermentation, purification, and crystallization. The process requires high-level technical expertise, and the product must meet strict quality standards to ensure its safety and efficacy. The market for L-homoproline is primarily driven by the pharmaceutical industry, with demand from both drug manufacturers and research institutions.

As a leading supplier of L-homoproline, our company is committed to providing high-quality products to meet the needs of our customers. Our state-of-the-art manufacturing facilities and rigorous quality control processes ensure that our L-homoproline products meet the highest standards of purity and consistency. With a deep understanding of the pharmaceutical industry and its evolving needs, we strive to offer customized solutions to meet the unique requirements of our customers.

In conclusion, L-homoproline is an essential amino acid with significant potential as a therapeutic agent. With a growing demand in the pharmaceutical industry, it is essential for chemical and pharmaceutical intermediates suppliers to provide high-quality products that meet strict regulatory standards. Our company is dedicated to meeting this demand by providing top-quality L-homoproline products and exceptional customer service.

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