L-Carnitine
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names L-carnitine
Structure
CAS No. 541-15-1 Boiling Point (℃) N/A
Molecular Weight 161.199 Melting Point (℃) 197-212 °C(lit.)
Density N/A Vapor Specific Gravity N/A
Molecular Formula C7H15NO3 Flash Point (℃) N/A
Solubility 2500 g/L (20 ºC) Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description L-carnitine is constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.Target: OthersL-Carnitine is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine can also be found in many foods, but red meats, such as beef and lamb, are the best choices for adding carnitine into the diet [1].
Target Human Endogenous Metabolite
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Marcovina, S.M., et al., Translating the basic knowledge of mitochondrial functions to metabolic therapy: role of L-carnitine. Transl Res, 2013. 161(2): p. 73-84.
Synonyms
L-(-)-Carnitine
karnitin
ST 198
EINECS 208-768-0
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium Hydroxide Inner Salt
Carnitrine
USPorFCC
(R)-Carnitine
Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, hydroxide, inner salt, L-
L-CARNITIN
3-Hydroxy-4-(trimethylammonio)butanoate
g-Trimethylammonium-b-hydroxybutirate
CAR-OH
Product Description
L-Carnitine is a naturally occurring amino acid that plays a critical role in energy metabolism. It is involved in the transport of fatty acids into the mitochondria, where they are oxidized to produce energy. L-Carnitine is produced in the human body from the amino acids lysine and methionine, but can also be obtained from dietary sources such as meat, fish, and dairy products.

L-Carnitine has been widely used as a dietary supplement due to its potential benefits in improving exercise performance, increasing fat burning, and promoting weight loss. It has also been investigated for its potential therapeutic effects in various medical conditions such as cardiovascular diseases, liver diseases, and neurological disorders.

From a pharmaceutical perspective, L-Carnitine is used as an important ingredient in a number of drugs for treating various diseases. For example, it is used in the treatment of primary and secondary carnitine deficiencies, chronic heart failure, and peripheral arterial disease.

The market demand for L-Carnitine has been steadily increasing in recent years, driven by the growing awareness of its health benefits and the rising prevalence of chronic diseases. According to a report by MarketsandMarkets, the global market for L-Carnitine is expected to reach USD 202.3 million by 2025, with a CAGR of 4.5% during the forecast period.

As a chemical product, L-Carnitine is mainly produced through chemical synthesis or microbial fermentation processes. The production process involves the use of various raw materials, including lysine, methionine, and trimethylamine. The quality and purity of L-Carnitine are critical to its efficacy and safety as a pharmaceutical ingredient.

In terms of the supply chain, L-Carnitine is typically supplied by chemical manufacturers to pharmaceutical companies or dietary supplement manufacturers. The price of L-Carnitine can be affected by various factors, such as the availability of raw materials, production costs, and market demand.

In conclusion, L-Carnitine is a versatile amino acid with a range of potential health benefits and pharmaceutical applications. Its market demand is expected to continue growing, driven by the increasing prevalence of chronic diseases and the growing awareness of its health benefits. As a chemical product, the quality and purity of L-Carnitine are critical to its efficacy and safety, and its production involves a complex supply chain that involves various upstream and downstream players in the pharmaceutical and dietary supplement industries.

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