L-Asparagine monohydrate
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names L-Asparagine monohydrate
Structure
CAS No. 5794-13-8 Boiling Point (℃) 438ºC at 760 mmHg
Molecular Weight 150.133 Melting Point (℃) 233-235 °C(lit.)
Density 1,543 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C4H10N2O4 Flash Point (℃) 218.7ºC
Solubility 30 g/L (20 ºC) Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
Target Human Endogenous Metabolite
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.
Synonyms
MFCD00151038
H-Asn-OH.H2O
L-ASPARAGINE H20
Asparagen
L-ASPARAGINE H2O
ASPARAGINE H2O
L-Asp.H2O
H-L-ASN-OH H2O
L-Asparagin,Monohydrat
D-Asparagine hydrate (1:1)
(2R)-2,4-Diamino-4-oxobutanoic acid hydrate
Product Description
L-Asparagine monohydrate is a naturally occurring amino acid commonly used in the pharmaceutical industry. It is an important raw material for the production of antibiotics, chemotherapeutic agents, and other pharmaceuticals. This article will analyze the L-Asparagine monohydrate market from the perspective of its medical uses, upstream and downstream of pharmaceutical grade, and the supply chain of chemical manufacturers.

Medical Uses:
L-Asparagine monohydrate is commonly used as an amino acid supplement in parenteral and enteral nutrition. It is also an essential component in the production of some chemotherapeutic agents. L-Asparagine monohydrate can also act as a neurotransmitter and has shown some promise in the treatment of neurological disorders such as Alzheimer's disease.

Pharmaceutical Grade Upstream and Downstream:
The upstream of pharmaceutical grade L-Asparagine monohydrate includes the production of L-Aspartic Acid, which is then converted to L-Asparagine through enzymatic reactions. The downstream of pharmaceutical grade L-Asparagine monohydrate includes the production of antibiotics, chemotherapeutic agents, and other pharmaceuticals.

Supply Chain:
The supply chain of L-Asparagine monohydrate involves the production of L-Aspartic Acid and its subsequent conversion to L-Asparagine monohydrate. The production of L-Aspartic Acid can occur through fermentation or chemical synthesis. Chemical manufacturers may produce L-Asparagine monohydrate as an isolated product or as part of a larger portfolio of amino acids.

Market Overview:
The L-Asparagine monohydrate market is expected to grow due to increasing demand from the pharmaceutical industry. The increasing prevalence of neurological disorders such as Alzheimer's disease is expected to drive demand for L-Asparagine monohydrate in the coming years. Furthermore, the increasing use of amino acids in the food and beverage industry is also expected to drive demand for L-Asparagine monohydrate.

Conclusion:
L-Asparagine monohydrate is an important amino acid used in the pharmaceutical industry, and its demand is expected to grow due to increasing demand from the pharmaceutical and food and beverage industries. The supply chain of L-Asparagine monohydrate involves the production of L-Aspartic Acid and its subsequent conversion to L-Asparagine monohydrate. As a result, chemical manufacturers play a critical role in the supply of L-Asparagine monohydrate.

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