L-Alanine

Specifications

N/A

Packing & Storage

Packing
Storage	Powder -20°C 3 years 4°C 2 years；In solvent -80°C 6 months, -20°C 1 month
Shipping	Room temperature in continental US; may vary elsewhere

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General Information

Chemical & Physical Properties

Safety Information

Synthetic Route

Biological Activity

Common Names	L-Alanine
Structure
CAS　No.	56-41-7	Boiling Point (℃)	212.9±23.0 °C at 760 mmHg
Molecular Weight	89.093	Melting Point (℃)	314.5 °C (dec.)(lit.)
Density	1.2±0.1 g/cm3	Vapor Specific Gravity	N/A
Molecular Formula	C3H7NO2	Flash Point (℃)	82.6±22.6 °C
Solubility	166.5 g/L (25 ºC)	Autoignition Temperature (℃)	N/A

Personal Protective Equipment		Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes		T+:Very toxic
Safety Phrases		S1-S28-S45
RIDADR		NONH for all modes of transport
WGK Germany		3
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Sore throat.	Use local exhaust or breathing protection.	Fresh air, rest.
Skin	Redness. Burning sensation. Itching.	Protective gloves.	Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes	Redness. Pain.	Wear safety goggles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Abdominal pain. Nausea. Vomiting.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.

Description	L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
Target	Human Endogenous Metabolite
In Vitro	The viability of both hiPSCs, 201B7 cells and ehiPSCs decrease with an increase in L-Alanine concentration, and reach 7.5±1.3% and 3.7±0.7% respectively at 1.2 M of L-Alanine. On the other hand, no decrease in the viability of hFBs and hSkMCs are observed. Although the viability of iCMs slightly decreases along with the increase of the L-Alanine concentration, viability of iCMs at 1.2 M concentration of L-Alanine, 49.4±6.9%, is significantly higher than that of undifferentiated iPSCs, 201B7 cells and ehiPSCs (p< 0.01). The viability of hiPSCs, 201B7 cells and ehiPSCs, drastically decrease even after 2 or 4 h treatment. In contrast, the viability of hFBs fails to decrease at 1, 2, and 4 h and shows a small decrease at 24 h treatment. The viability of 201B7 cells in suspension culture decreases to 11.8±6.0% following treatment with 1.2 M L-Alanine for 2 h, whereas that of hFBs is 72.9±14.2%[1].
References	[1]. Nagashima T, et al. Selective Elimination of Human Induced Pluripotent Stem Cells Using Medium with High Concentration of L-Alanine. Sci Rep. 2018 Aug 20;8(1):12427.

Synonyms

L-ARANINE
MFCD00064410
Fmoc-L-Ala-OH
H-L-ALA-OH
H-ALA-OH
L-ALA
ALANINE
ALA
L-Alanine

Product Description

L-Alanine is a non-essential amino acid that is commonly used as a dietary supplement and food additive. As a building block of protein, L-alanine is a crucial component in the growth and repair of muscles, making it popular among athletes and bodybuilders.
L-Alanine is often added to sports drinks and protein supplements due to its ability to enhance endurance and reduce muscle fatigue. It is also commonly used in the food industry as a flavor enhancer, particularly in baked goods, candies, and other sweet treats.
In addition to its role in muscle growth and repair, L-alanine is also believed to play a role in regulating blood sugar levels and supporting a healthy immune system. Some research suggests that L-alanine may even have potential anti-cancer properties, though more research is needed in this area.
As a food additive, L-alanine is generally regarded as safe by regulatory agencies such as the US Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA). It is generally well-tolerated by most people, though high doses may cause digestive upset in some individuals.
Overall, L-alanine is a versatile and widely used amino acid with a variety of potential health benefits. Whether you're an athlete looking to enhance your performance or simply looking to add some flavor to your favorite foods, L-alanine is a safe and effective option.

Pharmaceutical Grade	Protecting Reagent	Protected Amino Acids
Food Grade	Feed Grade	Amino Acid Salts And Derivatives

Pharmaceutical Grade	Protecting Reagent	Protected Amino Acids
Food Grade	Feed Grade	Amino Acid Salts And Derivatives