L-Lysine Hydrochloride
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names L-Lysine hydrochloride
Structure
CAS No. 657-27-2 Boiling Point (℃) 311.5ºC at 760 mmHg
Molecular Weight 182.648 Melting Point (℃) 263 °C (dec.)(lit.)
Density N/A Vapor Specific Gravity N/A
Molecular Formula C6H15ClN2O2 Flash Point (℃) 142.2ºC
Solubility 65 g/100 mL (20 ºC) Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro L-lysine treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhances antioxidant activity. Pre- or post-treatment with L-lysine leads to significant decreases in the levels of malondialdehyde and nitric oxide, while significant enhancement is observed in the activities of antioxidant enzymes (superoxide dismutase, catalase, and glutathione peroxidase) and glutathione[1]. L-lysine supplementation almost completely ameliorates vascular calcification. Dietary L-lysine strongly suppresses plasma intact parathyroid hormone in adenine rats and supports a proper bone-vascular axis. The conserved orientation of the femoral apatite in group Lys also evidences the bone-protective effects of L-lysine. Dietary L-lysine elevates plasma alanine, proline, arginine, and homoarginine but not lysine[2]. The dose-dependent delay in gastric emptying observed in rats is confirmed in humans with an increase in halftime of gastric emptying of 4 min/g L-lysine. Moreover, a dose-dependent increase in intestinal fluid accumulation is observed (0.4 mL/min/g L-lysine)[3].
References [1]. Al-Malki AL, et al. Suppression of acute pancreatitis by L-lysinein mice. BMC Complement Altern Med. 2015 Jun 23;15:193. [2]. Shimomura A, et al. Dietary L-lysineprevents arterial calcification in adenine-induced uremic rats. J Am Soc Nephrol. 2014 Sep;25(9):1954-65. [3]. Baruffol C, et al. L-lysine dose dependently delays gastric emptying and increases intestinal fluid volume in humans and rats. Neurogastroenterol Motil. 2014 Jul;26(7):999-1009.
Synonyms
H-Lys-OH.HCl
MFCD00064564
L-Lysinehydrochloride
(2S)-2,6-Diaminohexanoic acid monohydrochloride
L-Lysine, monohydrochloride
L-LYS HCL
Lysine hydrochloride
L-Lysine HCl
LYSINE-L HCL
L-Lysine hydrochloride
Product Description
L-Lysine hydrochloride is a highly purified form of the essential amino acid L-lysine, commonly used as a food additive in the food industry. It is produced by the hydrochlorination of L-lysine, resulting in the formation of L-lysine hydrochloride crystals, which are then refined to a fine powder.
As an essential amino acid, L-lysine cannot be synthesized by the human body and must be obtained from the diet. L-lysine is essential for protein synthesis, tissue repair, and the production of collagen, an important component of skin, tendons, and bones. In the food industry, L-lysine hydrochloride is added to a variety of foods, including meats, dairy products, and processed foods, as a nutritional supplement to increase the protein content and improve the quality of the protein.
L-lysine hydrochloride has several benefits when used as a food additive. It can improve the nutritional value of foods by increasing the protein content and improving the quality of the protein. It also has the ability to enhance the flavor and aroma of foods, making them more appealing to consumers. Additionally, L-lysine hydrochloride can act as a preservative, helping to prevent spoilage and extend the shelf life of foods.
L-lysine hydrochloride is generally recognized as safe (GRAS) by the US Food and Drug Administration (FDA) and has been approved for use in foods for many years. It is important to note, however, that excessive consumption of L-lysine can cause adverse effects, such as nausea, diarrhea, and abdominal cramps.
In conclusion, L-lysine hydrochloride is a valuable food additive that can improve the nutritional value, flavor, and shelf life of foods. It is commonly used in the food industry and has been shown to be safe for consumption in appropriate amounts.
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