Glycyl-L-leucine
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names H-Gly-Leu-OH
Structure
CAS No. 869-19-2 Boiling Point (℃) 410.4±30.0 °C at 760 mmHg
Molecular Weight 188.224 Melting Point (℃) 233-235 °C(lit.)
Density 1.1±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C8H16N2O3 Flash Point (℃) 202.0±24.6 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description Glycyl-l-leucine is a dipeptide that can be a common substrate for glycyl-leucine dipeptidase.
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Ganapathy V, et al. Interaction of amino acids with glycl-L-leucine hydrolysis and transport in monkey small intestine. Clin Sci (Lond). 1979 Dec;57(6):521-7.
Synonyms
Leucine, N-glycyl-, L-
Gly-L-Leu-OH
L-Leucine, N-glycyl-
EINECS 212-785-9
L-Leucine, glycyl-
DL-Leucine, N-glycyl-
Gly-Leu
L-Leucine,N-glycyl
Glycinyl-l-leucine
Glycyl-L-leucine
Glycylleucine
(2S)-2-[(Aminoacetyl)amino]-4-methylpentanoic acid
Product Description
Introduction: Glycyl-L-Leucine is a significant chemical compound with diverse applications in the chemical industry. This product introduction aims to provide an overview of Glycyl-L-Leucine, covering its raw materials, production process, market trends, and the current status of amino acids in the industry.

Raw Materials: Glycyl-L-Leucine is synthesized using glycine and L-leucine as the primary raw materials. Glycine and L-leucine serve as the precursors for the synthesis of Glycyl-L-Leucine.

Production Process: The production process of Glycyl-L-Leucine involves the following steps:
Step 1: Coupling - Glycine and L-leucine are coupled using suitable coupling agents or reagents to form Glycyl-L-Leucine. The coupling reaction is typically carried out in an appropriate solvent under controlled conditions.

Step 2: Purification - The resulting Glycyl-L-Leucine is purified and refined using techniques such as filtration, chromatography, or crystallization to achieve the desired level of purity.

Market Trends: The market demand for Glycyl-L-Leucine has been increasing due to its diverse applications in various industries. Here are some key market trends:
Pharmaceuticals: Glycyl-L-Leucine finds applications in the pharmaceutical industry. It can be used as a component in drug formulations or as a building block for the synthesis of peptide-based drugs. Peptides have gained significant attention as potential therapeutic agents due to their high specificity and targeted activity.

Nutraceuticals: Glycyl-L-Leucine is also used in the nutraceutical industry. It can be incorporated into dietary supplements or functional foods for its potential health benefits. Amino acids play a vital role in the body's metabolism and are essential for various physiological functions.

Current Status of Amino Acids: Amino acids are fundamental molecules in biochemistry and have a wide range of applications in various industries. They serve as building blocks for proteins and play critical roles in cellular processes. Glycine and L-leucine are among the important amino acids used in the production of Glycyl-L-Leucine and other compounds.

Conclusion: Glycyl-L-Leucine, synthesized by coupling glycine and L-leucine, holds significant value in the chemical industry. Its production involves the coupling of the amino acids, followed by purification. The market demand for Glycyl-L-Leucine is driven by its applications in the pharmaceutical and nutraceutical industries. Amino acids continue to be essential components in various industries, contributing to advancements in chemical applications, drug development, and nutrition science.

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