Gln-Trp
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names Ac-Leu-Asp-Gln-Trp-Phe-Gly-NH2
Structure
CAS No. 129809-09-2 Boiling Point (℃) 1379.9ºC at 760mmHg
Molecular Weight 805.877 Melting Point (℃) N/A
Density 1.322g/cm3 Vapor Specific Gravity N/A
Molecular Formula C39H51N9O10 Flash Point (℃) 788.4ºC
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description DL-Lysine (Lysine) is an α-amino acid that is used in the biosynthesis of proteins.
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.
Synonyms
Ac-L-Leu-L-Asp-L-Gln-L-Trp-L-Phe-Gly-NH2
NEUROKININ NK-2 RECEPTOR ANTAGONIST
R396
Product Description
Introduction: Gln-Trp, also known as glutamine-tryptophan, is a significant chemical compound with various applications in the chemical industry. This product introduction aims to provide an overview of Gln-Trp, covering its raw materials, production process, market trends, and the current status of amino acids in the industry.

Raw Materials: Gln-Trp is synthesized using amino acids glutamine (Gln) and tryptophan (Trp) as the primary raw materials. These amino acids serve as precursors for the synthesis of Gln-Trp.

Production Process: The production process of Gln-Trp involves the following steps:
Step 1: Peptide Synthesis - Glutamine and tryptophan amino acids are selectively combined using suitable coupling agents or enzymatic reactions to form the peptide structure of Gln-Trp. The coupling reaction is typically carried out in an appropriate solvent under controlled conditions.

Step 2: Purification - The synthesized Gln-Trp is purified using techniques such as chromatography, filtration, or crystallization to obtain the desired level of purity and remove any impurities or by-products.

Market Trends: The market demand for Gln-Trp has been growing due to its various applications in different industries. Here are some key market trends:
Pharmaceuticals: Gln-Trp finds applications in the pharmaceutical industry, particularly in the development of peptide-based drugs. It can serve as a building block for the synthesis of peptides with specific biological activities, targeting various disease pathways.

Nutraceuticals and Dietary Supplements: Gln-Trp is also utilized in the production of nutraceuticals and dietary supplements. It can contribute to the formulation of products aimed at promoting brain health, mood regulation, and overall well-being.

Current Status of Amino Acids: Amino acids play a vital role in various industries, including pharmaceuticals, food, and biotechnology. They serve as the building blocks of proteins and peptides, providing structure and functionality. Glutamine and tryptophan, the amino acids used in Gln-Trp synthesis, are essential in many physiological processes.

Conclusion: Gln-Trp, synthesized by selectively combining glutamine and tryptophan amino acids, is a valuable compound in the chemical industry. Its production involves peptide synthesis and subsequent purification. The market demand for Gln-Trp is driven by its applications in pharmaceuticals and nutraceuticals. Amino acids continue to be crucial components in various industries, contributing to the development of peptide-based products and advancements in health and well-being.

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