Fmoc-Glycine
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names Fmoc-Gly-OH
Structure
CAS No. 29022-11-5 Boiling Point (℃) 545.7±33.0 °C at 760 mmHg
Molecular Weight 297.305 Melting Point (℃) 174-175 °C(lit.)
Density 1.3±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C17H15NO4 Flash Point (℃) 283.8±25.4 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description Fmoc-Gly-OH (Fmoc glycine) is a Fmoc-protected glycine derivative, can be used for the synthesis of compounds[1].
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Xiaobing Wan, et al. Preparation method for carboxylate ester compound. WO2022134297A1 (compound 1q)
Synonyms
Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
MFCD00037140
FMOC-L-GLY-OH
EINECS 249-373-3
N-9-Fmoc-L-glycine
F-FMOC-GLYCINE
FMOC-GLY
FMOC-L-GLYCINE
{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}acetic acid
N-Fmoc-glycine
9-fluorenylmethyloxycarbonyl-Gly-OH
Glycine, N-((9H-fluoren-9-ylmethoxy)carbonyl)-
Product Description
Fmoc-Glycine is a cutting-edge product that combines amino acid protection with the field of chemical synthesis. With its unique properties and versatile applications, Fmoc-Glycine has gained significant recognition and widespread use in the international market. This product introduction aims to showcase the key features, advantages, and potential applications of Fmoc-Glycine, highlighting its crucial role in protecting amino acids and enabling efficient synthesis in the dynamic world of chemical engineering.

Enhanced Amino Acid Protection: Fmoc-Glycine offers enhanced protection for glycine, one of the fundamental amino acids. Its advanced protective group shields the amino group of glycine, preventing unwanted reactions and preserving the reactivity of other functional groups. This exceptional protection ensures the stability of glycine during chemical synthesis and enables the creation of complex molecules and peptides.

Versatile Applications: Fmoc-Glycine finds diverse applications in chemical synthesis processes. Its superior protection and compatibility make it an essential component in peptide synthesis, where it plays a vital role in protecting the N-terminus of peptides. Fmoc-Glycine is widely utilized in the pharmaceutical, biotechnology, and fine chemical industries, facilitating efficient synthesis and enabling the production of a wide range of compounds.

Facilitates Solid-Phase Synthesis: Fmoc-Glycine is particularly well-suited for solid-phase peptide synthesis (SPPS), a widely employed technique for peptide production. Its protective group allows for the stepwise assembly of peptides, ensuring the integrity of the amino acid sequence during the synthesis process. Fmoc-Glycine's compatibility with solid-phase supports and coupling reagents makes it an indispensable tool for the efficient and reliable production of peptides.

Global Market Impact: Fmoc-Glycine has made a significant impact on the global chemical market, emerging as a leading solution for amino acid protection. Its superior performance, consistent quality, and compatibility with various synthetic methodologies have gained recognition and trust from researchers, scientists, and industry professionals worldwide. The increasing demand for Fmoc-Glycine reflects its effectiveness in optimizing peptide synthesis and facilitating the development of novel drugs and biotechnological products.

Conclusion: Fmoc-Glycine represents a breakthrough in amino acid protection for chemical synthesis. Its advanced protective properties, versatile applications, and compatibility with solid-phase synthesis techniques make it an indispensable tool in modern chemical engineering. By utilizing Fmoc-Glycine, researchers and manufacturers can confidently protect glycine and other amino acids, enabling efficient synthesis and the production of complex molecules and peptides. Fmoc-Glycine is driving progress in the global chemical industry, facilitating the development of pharmaceuticals, biotechnology products, and fine chemicals. Choose Fmoc-Glycine for unrivaled amino acid protection and unlock new possibilities in chemical synthesis.

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