D-Tryptophan
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names D-Threonine
Structure
CAS No. 153-94-6 Boiling Point (℃) 447.9±35.0 °C at 760 mmHg
Molecular Weight 204.225 Melting Point (℃) 282-285ºC
Density 1.4±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C11H12N2O2 Flash Point (℃) 224.7±25.9 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide.
Target Human Endogenous Metabolite
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.
Synonyms
(2R)-2-amino-3-(1H-indol-3-yl)propanoic acid
(R)-a-Amino-3-indolepropionic Acid
Tryptophan
H-D-Trp-OH
(R)-a-Aminoindole-3-propanoic Acid
EINECS 205-819-9
D-α-Amino-3-indolepropionic acid
(R)-tryptophan
D-tryptophan
D-tryptophan zwitterion
(+)-Tryptophan
D(+)-Tryptophan
Product Description
D-tryptophan is a non-proteinogenic amino acid that has been widely used in the pharmaceutical industry for several decades. Its unique properties and chemical structure make it an attractive ingredient for many drug formulations, leading to a steady growth in demand for D-tryptophan in recent years.

One of the primary uses of D-tryptophan is as a precursor to the synthesis of various neurotransmitters and hormones, including serotonin, melatonin, and tryptamine. These compounds play crucial roles in the regulation of mood, sleep, and appetite, making D-tryptophan an essential ingredient in many psychiatric and neurological drugs.

D-tryptophan is also used in the production of a variety of other drugs, including anticancer agents, anti-inflammatory agents, and immunosuppressants. It is often used in combination with other amino acids and compounds to enhance the therapeutic effects of these drugs.

From a market perspective, the demand for D-tryptophan has been steadily increasing in recent years. This can be attributed to several factors, including the growing demand for high-quality pharmaceutical products, the increasing prevalence of mental health disorders, and the rising interest in natural and organic ingredients in the cosmetics industry.

In addition, the COVID-19 pandemic has also contributed to the demand for D-tryptophan, as it is used in the production of drugs that are being developed to combat the virus. This has led to an increase in demand for D-tryptophan from pharmaceutical companies worldwide.

Overall, the market for D-tryptophan is expected to continue to grow in the coming years. As the demand for high-quality pharmaceutical products and natural and organic cosmetics continues to increase, D-tryptophan is likely to become an increasingly popular ingredient. Additionally, the ongoing research into the potential use of D-tryptophan in the treatment of COVID-19 will also drive demand for this amino acid in the pharmaceutical industry.

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