D-Proline
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names D-Proline
Structure
CAS No. 344-25-2 Boiling Point (℃) 252.2±33.0 °C at 760 mmHg
Molecular Weight 115.131 Melting Point (℃) 223ºC
Density 1.2±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C5H9NO2 Flash Point (℃) 106.3±25.4 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description DL-Lysine (Lysine) is an α-amino acid that is used in the biosynthesis of proteins.
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.
Synonyms
(-)-Proline
(R)-(+)-Proline
H-D-PRO-OH
Proline
Proline, L-
(-)-(S)-proline
(2S)-proline
(R)-proline
(2S)-2-Pyrrolidinecarboxylic acid
(S)-2-Carboxypyrrolidine
(-)-2-Pyrrolidinecarboxylic acid
(−)-proline
(S)-proline
D-(+)-Prolin
EINECS 210-189-3
(2S)-pyrrolidine-2-carboxylic acid
Product Description
D-proline is a non-proteinogenic amino acid that is widely used in the pharmaceutical industry for various applications. Its unique chemical structure and properties make it an attractive ingredient for many drug formulations, leading to a steady growth in demand for D-proline in recent years.

One of the primary uses of D-proline is as a building block for peptide and protein synthesis. It is a key component in the production of various drugs, including immunosuppressants, antibiotics, and anti-inflammatory agents. D-proline is also used in the synthesis of enantiopure compounds, which have many applications in the pharmaceutical industry.

Another significant application of D-proline is in the production of cosmetics and personal care products. It is commonly used as a skin conditioning agent due to its ability to improve skin hydration and elasticity. D-proline is also used in hair care products, where it can help strengthen and protect hair fibers.

From a market perspective, the demand for D-proline has been steadily increasing in recent years. This can be attributed to several factors, including the growing demand for high-quality pharmaceutical products and the increasing focus on natural and organic ingredients in the cosmetics industry.

In addition, the COVID-19 pandemic has also contributed to the demand for D-proline, as it is used in the production of drugs that are being developed to combat the virus. This has led to an increase in demand for D-proline from pharmaceutical companies worldwide.

Overall, the market for D-proline is expected to continue to grow in the coming years. As the demand for high-quality pharmaceutical products and natural and organic cosmetics continues to increase, D-proline is likely to become an increasingly popular ingredient. Additionally, the ongoing research into the potential use of D-proline in the treatment of COVID-19 will also drive demand for this amino acid in the pharmaceutical industry.
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