D-phenylglycine methyl ester hydrochloride
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names H-D-Phg-OMe.HCl
Structure
CAS No. 19883-41-1 Boiling Point (℃) 238.9ºC at 760mmHg
Molecular Weight 201.65 Melting Point (℃) 189-191 °C(lit.)
Density 1.126g/cm3 Vapor Specific Gravity N/A
Molecular Formula C9H12ClNO2 Flash Point (℃) 104.7ºC
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description H-D-Phg-OMe.HCl is a Glycine (HY-Y0966) derivative[1].
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
Synonyms
(S)-2-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE
methyl (2S)-amino(phenyl)ethanoate hydrochloride (1:1)
D-phenylglycine methyl ester hydrochloride
Benzeneacetic acid, α-amino-, methyl ester, (αR)-, hydrochloride (1:1)
METHYL (2R)-2-AMINO-2-PHENYLACETATE HYDROCHLORIDE
EINECS 243-399-9
H-PH-Phg-Ome hydrochloride
S)-(+)-2-Phenylglycine methyl ester hydrochloride
D-Phenylycine Methyl Ester Hydrichloride
H-D-PHG-OME HCL
(R)-PGME hydrochloride
L-Phenylglycine methyl ester hydrochloride
Product Description
Introduction: D-Alanine Methyl Ester Hydrochloride is a valuable compound with diverse applications in various industries. This product introduction aims to provide a comprehensive overview of D-Alanine Methyl Ester Hydrochloride, covering its production process, wide-ranging applications, and promising market prospects. With its versatility and increasing demand, D-Alanine Methyl Ester Hydrochloride is poised to be a sought-after compound in the global market.

Production: D-Alanine Methyl Ester Hydrochloride is produced through a well-established chemical synthesis process. The manufacturing process involves the reaction of D-Alanine with methanol and subsequent treatment with hydrochloric acid to form D-Alanine Methyl Ester Hydrochloride. Stringent quality control measures are implemented throughout the production process to ensure the highest purity and consistency of the final product.

Applications: D-Alanine Methyl Ester Hydrochloride finds applications across various industries due to its unique properties:
a. Pharmaceutical Industry: D-Alanine Methyl Ester Hydrochloride serves as a valuable intermediate in the synthesis of pharmaceutical compounds. It is widely used in the production of drugs targeting various therapeutic areas, including antibiotics, antivirals, and anticancer agents. Its incorporation into pharmaceutical formulations enhances drug efficacy and stability.

b. Peptide Synthesis: D-Alanine Methyl Ester Hydrochloride is employed in peptide synthesis, particularly in the production of peptidomimetics and modified peptides. Its use enables the development of novel peptide-based therapeutics with enhanced properties such as improved stability and bioactivity.

c. Research and Biotechnology: D-Alanine Methyl Ester Hydrochloride plays a significant role in biochemical and biotechnological research. It serves as a building block in the synthesis of peptides, proteins, and other bioactive molecules. Its incorporation into peptide sequences allows researchers to study protein structure, function, and drug-target interactions.

Market Prospects: D-Alanine Methyl Ester Hydrochloride demonstrates promising market prospects due to the following factors:
a. Pharmaceutical Advancements: The continuous advancements in the pharmaceutical industry drive the demand for D-Alanine Methyl Ester Hydrochloride as a key intermediate in drug synthesis. The need for innovative therapeutic solutions and the growing demand for antibiotics contribute to its market growth.

b. Peptide-based Therapeutics: The increasing interest in peptide-based therapeutics, driven by their high specificity and efficacy, fuels the demand for D-Alanine Methyl Ester Hydrochloride in peptide synthesis. The development of novel peptide drugs for various diseases presents significant market opportunities.

c. Research and Development: The ongoing research activities in biochemistry, biotechnology, and drug discovery create a steady demand for D-Alanine Methyl Ester Hydrochloride. Its role in peptide synthesis and protein engineering positions it as a valuable tool in these fields.

Conclusion: D-Alanine Methyl Ester Hydrochloride is a versatile compound with significant production, diverse applications, and promising market prospects. Its involvement in pharmaceutical synthesis, peptide chemistry, and research applications underscores its wide-ranging utility. With the pharmaceutical advancements, the growing interest in peptide-based therapeutics, and ongoing research and development activities, D-Alanine Methyl Ester Hydrochloride is expected to experience substantial demand in the global market.

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