D-Leucine methyl ester hydrochloride
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names Methyl D-leucinate hydrochloride (1:1)
Structure
CAS No. 5845-53-4 Boiling Point (℃) 169.2ºC at 760 mmHg
Molecular Weight 181.66 Melting Point (℃) 150ºC
Density 0.955g/cm3 Vapor Specific Gravity N/A
Molecular Formula C7H16ClNO2 Flash Point (℃) 42.7ºC
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description (R)-methyl 2-amino-4-methylpentanoate hydrochloride is a leucine derivative[1].
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
Synonyms
Methyl D-leucinate hydrochloride (1:1)
[(2R)-1-methoxy-4-methyl-1-oxopentan-2-yl]azanium
MFCD00066115
D-Leucine, methyl ester, hydrochloride (1:1)
D-LEUCINE METHYL ESTER HYDROCHLORIDE SALT
Product Description
Introduction: D-Leucine Methyl Ester Hydrochloride is a valuable compound that holds immense potential in various industries. This product introduction aims to provide a comprehensive overview of D-Leucine Methyl Ester Hydrochloride, including its production process, diverse applications, and promising market prospects. With its unique properties and increasing demand, D-Leucine Methyl Ester Hydrochloride is poised to be a valuable asset in the global market.

Production: D-Leucine Methyl Ester Hydrochloride is typically synthesized through a well-established chemical process. The production involves the reaction of D-Leucine with methanol, followed by the addition of hydrochloric acid to form D-Leucine Methyl Ester Hydrochloride. Rigorous quality control measures are implemented during the production process to ensure the highest purity and consistency of the final product.

Applications: D-Leucine Methyl Ester Hydrochloride finds applications across various industries due to its unique properties:
a. Pharmaceutical Industry: D-Leucine Methyl Ester Hydrochloride serves as a crucial intermediate in the synthesis of pharmaceutical compounds. It is widely used in the production of drugs targeting various therapeutic areas, including cardiovascular health, muscle growth, and amino acid-based formulations. Its inclusion in pharmaceutical formulations enhances drug stability, solubility, and bioavailability.

b. Food and Beverage Industry: D-Leucine Methyl Ester Hydrochloride is employed in the food and beverage industry as a flavor enhancer and nutritional supplement. It contributes to the umami taste profile, providing a savory and meaty flavor to food products. Additionally, it is utilized in sports nutrition supplements to support muscle recovery and protein synthesis.

c. Research and Biotechnology: D-Leucine Methyl Ester Hydrochloride plays a vital role in biochemical and biotechnological research. It serves as a building block in the synthesis of peptides, proteins, and other bioactive molecules. Its incorporation into peptide sequences allows researchers to study protein structure, function, and enzymatic activities.

Market Prospects: D-Leucine Methyl Ester Hydrochloride demonstrates promising market prospects due to the following factors:
a. Pharmaceutical Advancements: The continuous advancements in the pharmaceutical industry drive the demand for D-Leucine Methyl Ester Hydrochloride as a key intermediate in drug synthesis. The development of novel therapeutics and the increasing focus on personalized medicine contribute to its market growth.

b. Growing Health and Fitness Industry: The health and fitness industry is witnessing significant growth globally. D-Leucine Methyl Ester Hydrochloride's role in muscle growth and protein synthesis makes it appealing for use in sports nutrition and dietary supplements. The increasing consumer awareness regarding fitness and wellness further fuels its market potential.

c. Research and Development: Ongoing research activities in biochemistry, biotechnology, and pharmaceutical sciences create a sustained demand for D-Leucine Methyl Ester Hydrochloride. Its versatile applications in peptide synthesis, protein engineering, and enzymology position it as a valuable tool in these fields.

Conclusion: D-Leucine Methyl Ester Hydrochloride is a valuable compound with significant production, diverse applications, and promising market prospects. Its involvement in pharmaceutical synthesis, food flavoring, and research applications highlights its wide-ranging utility. With the advancements in the pharmaceutical industry, the growth of the health and fitness sector, and ongoing research and development activities, D-Leucine Methyl Ester Hydrochloride is expected to experience substantial demand in the global market.

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