D-Glutamic Acid

Specifications

N/A

Packing & Storage

Packing
Storage	Powder -20°C 3 years 4°C 2 years；In solvent -80°C 6 months, -20°C 1 month
Shipping	Room temperature in continental US; may vary elsewhere

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General Information

Chemical & Physical Properties

Safety Information

Synthetic Route

Biological Activity

Common Names	D-Glutamic acid
Structure
CAS　No.	6893-26-1	Boiling Point (℃)	333.8±32.0 °C at 760 mmHg
Molecular Weight	147.129	Melting Point (℃)	200-202ºC
Density	1.4±0.1 g/cm3	Vapor Specific Gravity	N/A
Molecular Formula	C5H9NO4	Flash Point (℃)	155.7±25.1 °C
Solubility	N/A	Autoignition Temperature (℃)	N/A

Personal Protective Equipment		Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes		T+:Very toxic
Safety Phrases		S1-S28-S45
RIDADR		NONH for all modes of transport
WGK Germany		3
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Sore throat.	Use local exhaust or breathing protection.	Fresh air, rest.
Skin	Redness. Burning sensation. Itching.	Protective gloves.	Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes	Redness. Pain.	Wear safety goggles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Abdominal pain. Nausea. Vomiting.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.

Description	D-glutamic acid, an enantiomer of L- glutamic acid, is widely used in pharmaceuticals and foods.
Target	Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro	Various d-amino acids, such as D-serine, D-aspartic acid (D-Asp), and D-glutamic acid (D-Glu) are widely found in mammals including human beings and they are now thought to be the candidates of novel physiologically active substances and/or biomarkers[1]. D-[Asp/Glu] (4 mg/mL) inhibits IgE binding (75%) to peanuts while D-Glu, D-Asp has no inhibitory effect. IgE is specific for D-[Asp/Glu] and may have the potential for removing IgE or reducing IgE binding to peanut allergens[2].
References	[1]. Han H, et al. Changes in D-aspartic acid and D-glutamic acid levels in the tissues and physiological fluids of mice with various D-aspartate oxidase activities. J Pharm Biomed Anal. 2015 Dec 10;116:47-52. [2]. Chung SY, et al. IgE binding to peanut allergens is inhibited by combined D-aspartic and D-glutamic acids. Food Chem. 2015 Jan 1;166:248-53.

Synonyms

H-D-Glu-OH
Glutamic acid, D-
MFCD00063112
D(-)-Glutamic acid
glutamic acid D-form
EINECS 230-000-8
δ-Glutamic acid
hydrogen D-glutamate
d-Glu
(R)-(-)-GLUTAMIC ACID
R-(-)-Glutamic acid
(2R)-2-aminopentanedioic acid
D-Glutamic acid
D(-)-Glutamicacid

Product Description

D-glutamic acid is a non-essential amino acid that has many applications in the pharmaceutical industry. It is commonly used in the production of drugs used to treat various neurological disorders, as well as supplements used to improve athletic performance. In this analysis, we will explore the uses of D-glutamic acid in medicine, the upstream and downstream industries involved in its production, the current market trends, and the major chemical suppliers.
Uses of D-glutamic acid in medicine:
D-glutamic acid has been shown to have a number of potential medical uses. It is commonly used as an ingredient in drugs used to treat various neurological disorders such as Alzheimer's disease, Parkinson's disease, and epilepsy. It is also used in the production of antibiotics and antiviral drugs.
Upstream and downstream industries:
The production of D-glutamic acid involves a number of upstream and downstream industries. The primary raw material used in the production of D-glutamic acid is L-glutamic acid, which is produced through the fermentation process. Other upstream industries involved in the production of D-glutamic acid include the production of amino acids and other raw materials used in the fermentation process.
Downstream industries include the production of various pharmaceuticals that use D-glutamic acid as an ingredient. These include drugs used to treat neurological disorders, as well as supplements used to improve athletic performance. The downstream industry also includes the production of food additives that contain D-glutamic acid, such as monosodium glutamate (MSG).
Market trends:
The market for D-glutamic acid is expected to grow significantly in the coming years. This growth is primarily driven by the increasing demand for drugs used to treat various neurological disorders and the growing interest in supplements that improve athletic performance. The use of D-glutamic acid in food additives is also expected to contribute to the growth of the market.
Chemical suppliers:
There are a number of chemical suppliers that produce and sell D-glutamic acid. Some of the major suppliers include Ajinomoto, Kyowa Hakko Bio, and CJ CheilJedang. These companies produce D-glutamic acid using various methods, including fermentation and chemical synthesis.
Conclusion:
D-glutamic acid is an important raw material for the production of a number of pharmaceutical products and food additives. Its potential benefits make it a valuable ingredient in the medical and food industries. The growing demand for drugs used to treat neurological disorders and supplements used to improve athletic performance is expected to drive the growth of the market in the coming years.

Pharmaceutical Grade	Protecting Reagent	Protected Amino Acids
Food Grade	Feed Grade	Amino Acid Salts And Derivatives

Pharmaceutical Grade	Protecting Reagent	Protected Amino Acids
Food Grade	Feed Grade	Amino Acid Salts And Derivatives