D-Glutamic acid dimethyl ester hydrochloride
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names H-D-Glu-(OMe)-Ome HCL
Structure
CAS No. 27025-25-8 Boiling Point (℃) N/A
Molecular Weight 211.643 Melting Point (℃) 143ºC
Density N/A Vapor Specific Gravity N/A
Molecular Formula C7H14ClNO4 Flash Point (℃) N/A
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description Dimethyl D-glutamate hydrochloride is a glutamic acid derivative[1].
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
Synonyms
H-D-Glu(OMe)-OMe.HCl
D-Glutamic Acid Dimethyl Ester Hydrochloride
H-D-Glu(Ome)-Ome HCl
D-Glu(Me)-OMe*HCl
L-Glutamic acid, dimethyl ester, hydrochloride (1:1)
dimethyl (-)-(R)-glutamate hydrochloride
Dimethyl D-glutamate hydrochloride (1:1)
H-D-Glu(OMe)OMe hydrochloride
Dimethyl L-glutamate hydrochloride (1:1)
Dimethyl D-Glutamate Hydrochloride
dimethyl (R)-2-aminopentanedioate hydrochloride
H-D-Glu(OMe)-OMe·HCl
D-Glutamic acid, dimethyl ester, hydrochloride (1:1)
H-D-Glu-(OMe)-Ome HCL
Product Description
Introduction: D-Glutamic Acid Dimethyl Ester Hydrochloride is a chemical compound derived from D-glutamic acid, a non-essential amino acid with important biological functions. This product is widely used in the pharmaceutical, research, and chemical industries due to its unique properties and versatile applications.

Raw Materials: D-Glutamic Acid Dimethyl Ester Hydrochloride is synthesized using high-quality raw materials, including D-glutamic acid and methanol. D-glutamic acid, obtained through appropriate chemical reactions or enzymatic methods, serves as the starting material for the synthesis. Methanol, a commonly used solvent and reagent in organic synthesis, is used for esterification to produce D-Glutamic Acid Dimethyl Ester.

Production Process: The production of D-Glutamic Acid Dimethyl Ester Hydrochloride involves controlled steps to ensure consistent product quality. D-glutamic acid is first obtained from a reliable source and then reacted with methanol under specific conditions. The esterification reaction is carefully monitored, and the resulting D-Glutamic Acid Dimethyl Ester is converted into the hydrochloride salt form for improved stability and solubility. Purification techniques such as crystallization and filtration are employed to obtain a pure and crystalline form of D-Glutamic Acid Dimethyl Ester Hydrochloride.

Market Trends: D-Glutamic Acid Dimethyl Ester Hydrochloride has gained significant attention in the pharmaceutical and research industries due to its potential applications. In the pharmaceutical sector, it serves as a valuable intermediate for the synthesis of various drug molecules targeting specific diseases and disorders. It can be used in the development of pharmaceutical intermediates and active pharmaceutical ingredients (APIs). In research, D-Glutamic Acid Dimethyl Ester Hydrochloride finds applications in the study of enzyme kinetics, peptide synthesis, and drug delivery systems. The market demand for D-Glutamic Acid Dimethyl Ester Hydrochloride is driven by the continuous need for innovative compounds in drug discovery and research.

Amino Acid Status: D-Glutamic acid is a non-essential amino acid that plays important roles in protein synthesis, neurotransmission, and metabolism. By esterifying D-glutamic acid with methanol, D-Glutamic Acid Dimethyl Ester Hydrochloride offers enhanced stability and solubility, making it suitable for various applications in the pharmaceutical and chemical industries.

Conclusion: D-Glutamic Acid Dimethyl Ester Hydrochloride is a valuable compound with diverse applications in the pharmaceutical, research, and chemical industries. Its synthesis from high-quality raw materials and stringent production processes ensure consistent product quality. The market demand for D-Glutamic Acid Dimethyl Ester Hydrochloride is expected to continue growing due to its unique properties and potential applications in drug discovery, pharmaceutical synthesis, and research endeavors. With its versatile applications and potential contributions to pharmaceutical development and scientific advancements, D-Glutamic Acid Dimethyl Ester Hydrochloride provides a valuable option for formulation and application in different industries, supporting drug synthesis, peptide chemistry, and research endeavors.

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