D-Diethyl glutamate hydrochloride
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names diethyl 2-aminopentanedioate,hydrochloride
Structure
CAS No. 1001-19-0 Boiling Point (℃) N/A
Molecular Weight 239.697 Melting Point (℃) 113-115 ºC
Density N/A Vapor Specific Gravity N/A
Molecular Formula C9H18ClNO4 Flash Point (℃) N/A
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description DL-Lysine (Lysine) is an α-amino acid that is used in the biosynthesis of proteins.
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.
Synonyms
Diethyl D-glutamate hydrochloride
Product Description
Introduction: D-Diethyl Glutamate Hydrochloride is a chemical compound derived from D-glutamic acid, an amino acid with various biological functions. It is widely used in the pharmaceutical, research, and chemical industries due to its unique properties and potential applications.

Raw Materials: D-Diethyl Glutamate Hydrochloride is synthesized using high-quality raw materials, including D-glutamic acid and ethanol. D-glutamic acid, obtained through appropriate chemical reactions or enzymatic processes, serves as the starting material for the synthesis. Ethanol, a common solvent and reagent, is used for esterification to produce D-Diethyl Glutamate.

Production Process: The production of D-Diethyl Glutamate Hydrochloride involves carefully controlled steps to ensure consistent product quality. D-glutamic acid is first obtained from a reliable source and then reacted with ethanol under specific conditions. The esterification reaction is closely monitored, and the resulting D-Diethyl Glutamate is converted into the hydrochloride salt form for improved stability and solubility. Purification techniques such as crystallization and filtration are employed to obtain a pure and crystalline form of D-Diethyl Glutamate Hydrochloride.

Market Trends: D-Diethyl Glutamate Hydrochloride has gained significant interest in the pharmaceutical and research industries due to its potential applications. It serves as a valuable intermediate for the synthesis of various drug molecules and pharmaceutical intermediates. It can be used in the development of new drugs, especially those targeting the glutamate system. The market demand for D-Diethyl Glutamate Hydrochloride is driven by the continuous need for innovative compounds in drug discovery and research.

Amino Acid Status: D-glutamic acid is a non-essential amino acid that plays important roles in protein synthesis, neurotransmission, and cellular metabolism. By esterifying D-glutamic acid with ethanol, D-Diethyl Glutamate Hydrochloride offers enhanced stability and solubility, making it suitable for various applications in the pharmaceutical and chemical industries.

Conclusion: D-Diethyl Glutamate Hydrochloride is a valuable compound with diverse applications in the pharmaceutical, research, and chemical industries. Its synthesis from high-quality raw materials and stringent production processes ensure consistent product quality. The market demand for D-Diethyl Glutamate Hydrochloride is expected to continue growing due to its unique properties and potential applications in drug discovery, pharmaceutical synthesis, and research endeavors. With its versatile applications and potential contributions to pharmaceutical development and scientific advancements, D-Diethyl Glutamate Hydrochloride provides a valuable option for formulation and application in different industries, supporting drug synthesis, neurological research, and other related fields.

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