D-Cystine
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names D-Cystine
Structure
CAS No. 349-46-2 Boiling Point (℃) 468.2±45.0 °C at 760 mmHg
Molecular Weight 240.301 Melting Point (℃) 260ºC
Density 1.6±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C6H12N2O4S2 Flash Point (℃) 237.0±28.7 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description D-Cystine is the D-enantiomer of L-Cystine. D-Cystine inhibits L-aspartate-β-semialdehyde dehydrogenase (ASADH) from Escherichia coli[1].
Target IC50: L-aspartate-β-semialdehyde dehydrogenase (ASADH)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Emilio Alvarez, et al. L-cystine inhibits aspartate-beta-semialdehyde dehydrogenase by covalently binding to the essential 135Cys of the enzyme. Biochim Biophys Acta. 2004 Jan 14;1696(1):23-9.
Synonyms
D,L-cystine
meso-Cystine
UNII:06681CV9GH
(S)-Cystine
Cystine, D-
D(+)-CYSTINE
MFCD00002610
D-Cystine
D-CYSTINE CRYSTALLINE
H-D-CYSTINE
EINECS 206-486-2
H-D-(Cys)2-OH
Product Description
D-Cystine is a non-essential amino acid that can be synthesized in the human body by the oxidation of cysteine. It is a dimer of two cysteine molecules linked by a disulfide bond. D-Cystine has various applications in the pharmaceutical, nutritional, and cosmetic industries.
In the pharmaceutical industry, D-Cystine is used as a building block for the synthesis of cysteine-containing drugs, such as N-acetylcysteine, which is used to treat respiratory disorders. It is also used as a raw material for the production of glutathione, an important antioxidant that protects cells from damage caused by reactive oxygen species.
In the nutritional industry, D-Cystine is used as a dietary supplement to enhance protein synthesis and promote muscle growth. It is also used in sports nutrition products to help athletes increase their muscle mass and improve their athletic performance.
In the cosmetic industry, D-Cystine is used as an ingredient in hair care products, such as shampoos and conditioners, to strengthen hair and promote hair growth. It is also used in skin care products to help reduce the appearance of wrinkles and fine lines.
The production of D-Cystine involves the chemical synthesis of cysteine followed by oxidation to form the disulfide bond. D-Cystine is available in the form of a white crystalline powder and is sold by various chemical suppliers.
The global market for D-Cystine is driven by the increasing demand for cysteine-containing drugs, the growing awareness of the importance of antioxidants in preventing diseases, and the rising demand for sports nutrition products. The major players in the D-Cystine market include Ajinomoto, Evonik Industries AG, and Wuxi Enovo Chemical Co., Ltd.
In conclusion, D-Cystine is a versatile amino acid with various applications in the pharmaceutical, nutritional, and cosmetic industries. Its production involves chemical synthesis and it is available in the form of a white crystalline powder. The global market for D-Cystine is expected to continue to grow in the coming years due to the increasing demand for cysteine-containing drugs, antioxidants, and sports nutrition products.
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