D-Cysteine

Specifications

N/A

Packing & Storage

Packing
Storage	Powder -20°C 3 years 4°C 2 years；In solvent -80°C 6 months, -20°C 1 month
Shipping	Room temperature in continental US; may vary elsewhere

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General Information

Chemical & Physical Properties

Safety Information

Synthetic Route

Biological Activity

Common Names	D-Cysteine
Structure
CAS　No.	921-01-7	Boiling Point (℃)	293.9±35.0 °C at 760 mmHg
Molecular Weight	121.158	Melting Point (℃)	230ºC
Density	1.3±0.1 g/cm3	Vapor Specific Gravity	N/A
Molecular Formula	C3H7NO2S	Flash Point (℃)	131.5±25.9 °C
Solubility	N/A	Autoignition Temperature (℃)	N/A

Personal Protective Equipment		Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes		T+:Very toxic
Safety Phrases		S1-S28-S45
RIDADR		NONH for all modes of transport
WGK Germany		3
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Sore throat.	Use local exhaust or breathing protection.	Fresh air, rest.
Skin	Redness. Burning sensation. Itching.	Protective gloves.	Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes	Redness. Pain.	Wear safety goggles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Abdominal pain. Nausea. Vomiting.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.

Description	D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of Escherichia coli growth. D-cysteine is mediated by D-amino acid oxidase to produce H2S and is a neuroprotectant against cerebellar ataxias. D-Cysteine could inhibit the growth and cariogenic virulence of dual-species biofilms formed by S. mutans and S. sanguinis[1][2][3].
Target	Human Endogenous Metabolite
In Vitro	DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References	[1]. Seki T. Availability of D-cysteine as a protectant for cerebellar neurons. Nihon Yakurigaku Zasshi. 2019;154(3):133-137. [2]. Soutourina J, et al. Role of D-cysteine desulfhydrase in the adaptation of Escherichia coli to D-cysteine. J Biol Chem. 2001 Nov 2;276(44):40864-72. [3]. Guo X1, et al. Effect of D-cysteine on dual-species biofilms of Streptococcus mutans and Streptococcus sanguinis. Sci Rep. 2019 Apr 30;9(1):6689.

Synonyms

(2S)-2-amino-3-mercaptopropanoic acid
S-cysteine
(D,L)-H-Cys-OH
D-Cystein
MFCD00066461
D-Amino-3-mercaptopropionic acid
(S)-2-amino-3-mercaptopropanoic acid
(2S)-2-amino-3-sulfanylpropanoic acid
EINECS 213-062-0
(S)-2-Amino-3-mercaptopropionic acid
Cysteine,D
2-amino-3-sulfopropionic acid
D-Zystein
Cysteine, D-
H-D-Cys-OH

Product Description

D-cysteine is a non-essential amino acid, which means it can be synthesized by the human body and is also obtained through dietary sources. D-cysteine is an isomer of L-cysteine and has been found to have unique properties and potential therapeutic applications.
Medical uses: D-cysteine has been found to have antioxidant and neuroprotective effects. It has also been investigated for its potential role in the treatment of various neurological disorders such as Parkinson's disease, Alzheimer's disease, and schizophrenia. D-cysteine is also used in the production of the drug acetylcysteine, which is used to treat respiratory conditions such as chronic obstructive pulmonary disease (COPD).
Market trends: The demand for D-cysteine is growing due to its potential therapeutic applications and the increasing awareness of its benefits. The market for D-cysteine is expected to grow in the coming years due to its use in the pharmaceutical and nutraceutical industries. The increasing demand for dietary supplements and functional foods is also expected to drive the growth of the D-cysteine market.
Upstream and downstream: D-cysteine is derived from L-cysteine through a process called racemization. L-cysteine is obtained through the hydrolysis of various proteins, such as wool, hair, and feathers. The production of D-cysteine involves the use of enzymes, which can be obtained from natural sources or through recombinant DNA technology. D-cysteine is used in the production of acetylcysteine, which is produced by acetylation of L-cysteine. Acetylcysteine is used in the treatment of respiratory conditions.
Chemical suppliers: D-cysteine is produced by various chemical companies around the world. The production of D-cysteine involves the use of enzymes, which can be obtained from natural sources or through recombinant DNA technology. Some of the major chemical suppliers of D-cysteine include Ajinomoto Co., Inc., Kyowa Hakko Bio Co., Ltd., and Nippon Rika Co., Ltd.
In conclusion, D-cysteine is a non-essential amino acid that has potential therapeutic applications. The market for D-cysteine is expected to grow in the coming years due to its use in the pharmaceutical and nutraceutical industries. The production of D-cysteine involves the use of enzymes, which can be obtained from natural sources or through recombinant DNA technology.

Pharmaceutical Grade	Protecting Reagent	Protected Amino Acids
Food Grade	Feed Grade	Amino Acid Salts And Derivatives

Pharmaceutical Grade	Protecting Reagent	Protected Amino Acids
Food Grade	Feed Grade	Amino Acid Salts And Derivatives