D-Arginine
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names D-Arginine
Structure
CAS No. 157-06-2 Boiling Point (℃) 367.6±52.0 °C at 760 mmHg
Molecular Weight 174.201 Melting Point (℃) 221-224ºC
Density 1.5±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C6H14N4O2 Flash Point (℃) 176.1±30.7 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description D-arginine (H-D-Arg-OH) is the D-isomer of arginine. Arginine is an α-amino acid that is used in the biosynthesis of proteins. D-Arginine is an inactive form of L-arginine[1].
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Eduardo Navarro , et al. Toxicological and Pharmacological Effects of D-arginine. Basic Clin Pharmacol Toxicol. 2005 Sep;97(3):149-54.
Synonyms
(R)-2-Amino-5-guanidinopentanoic acid
EINECS 205-866-5
H-D-Arg-OH
D-ARGININE BASE
R-(-)-ARGININE
D-ornithine, N-(diaminomethylene)-
(2R)-2-amino-5-guanidinopentanoic acid
D-Arg-OH
D-ARG.FREE BASE
D-2-Amino-5-guanidinovalerate
Product Description
D-Arginine is an essential amino acid that has many applications in the pharmaceutical industry, particularly in the production of drugs used to treat cardiovascular disease. In this analysis, we will explore the uses of D-Arginine in medicine, the upstream and downstream industries involved in its production, the current market trends, and the major chemical suppliers.
Uses of D-Arginine in medicine: D-Arginine has been shown to have a number of potential medical uses. It is commonly used as an ingredient in drugs used to treat cardiovascular disease, such as nitric oxide donors and angiotensin-converting enzyme (ACE) inhibitors. It has also been used in the treatment of erectile dysfunction and to improve athletic performance.
Upstream and downstream industries: The production of D-Arginine involves a number of upstream and downstream industries. The primary raw material used in the production of D-Arginine is L-Arginine, which is produced through the fermentation process. Other upstream industries involved in the production of D-Arginine include the production of amino acids and other raw materials used in the fermentation process.
Downstream industries include the production of various pharmaceuticals that use D-Arginine as an ingredient. These include drugs used to treat cardiovascular disease, as well as supplements used to improve athletic performance. The downstream industry also includes the production of animal feed supplements that contain D-Arginine.
Market trends: The market for D-Arginine is expected to grow significantly in the coming years. This growth is primarily driven by the increasing demand for drugs used to treat cardiovascular disease, as well as the growing interest in supplements that improve athletic performance. The use of D-Arginine in animal feed supplements is also expected to contribute to the growth of the market.
Chemical suppliers: There are a number of chemical suppliers that produce and sell D-Arginine. Some of the major suppliers include CJ CheilJedang, Ajinomoto, and Evonik. These companies produce D-Arginine using various methods, including fermentation and chemical synthesis.
Conclusion: D-Arginine is an important raw material for the production of a number of pharmaceutical products and animal feed supplements. Its potential benefits make it a valuable ingredient in the medical and food industries. The growing demand for drugs used to treat cardiovascular disease and supplements used to improve athletic performance is expected to drive the growth of the market in the coming years.
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