Boc-Glycylglycine Boc-Gly-Gly-OH
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names N-(tert-Butoxycarbonyl)glycylglycin
Structure
CAS No. 31972-52-8 Boiling Point (℃) 488.1±30.0 °C at 760 mmHg
Molecular Weight 232.234 Melting Point (℃) 126 °C(dec.)
Density 1.2±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C9H16N2O5 Flash Point (℃) 249.0±24.6 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description Boc-Gly-Gly-OH is a Glycine (HY-Y0966) derivative[1].
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
Synonyms
2-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]acetyl]amino]acetic acid
Glycine, N-[(1,1-dimethylethoxy)carbonyl]glycyl-
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}glycylglycine
N-(tert-Butoxycarbonyl)glycylglycin
N-(tert-butoxycarbonyl)glycylglycine
MFCD00038558
Boc-Gly-Gly-OH
Product Description
Introduction: Boc-Glycylglycine, also known as Boc-Gly-Gly-OH, is a significant chemical compound with various applications in the chemical industry. This product introduction aims to provide an overview of Boc-Glycylglycine, covering its raw materials, production process, market trends, and the current status of amino acids in the industry.

Raw Materials: Boc-Glycylglycine is synthesized using glycine and Boc anhydride as the primary raw materials. Glycine, an amino acid, and Boc anhydride (tert-butyloxycarbonyl anhydride) serve as the precursors for the synthesis of Boc-Glycylglycine.

Production Process: The production process of Boc-Glycylglycine involves the following steps:
Step 1: Protection - Glycine is protected by reacting it with Boc anhydride to form Boc-Glycine. This process protects the amino group of glycine and allows further reactions without unwanted side reactions.

Step 2: Coupling - Boc-Glycine is then coupled with glycine using suitable coupling agents or reagents to form Boc-Glycylglycine. The reaction is typically carried out in an appropriate solvent under controlled conditions.

Step 3: Deprotection - The Boc protecting group is removed from Boc-Glycylglycine using acid or base hydrolysis, resulting in the formation of Boc-Glycylglycine (Boc-Gly-Gly-OH).

Market Trends: The market demand for Boc-Glycylglycine has been increasing due to its versatile applications in various industries. Here are some key market trends:
Peptide Synthesis: Boc-Glycylglycine is commonly used in peptide synthesis as a building block to create more complex peptide structures. It serves as a link between other amino acids, enabling the creation of specific peptide sequences.

Pharmaceutical Research: Boc-Glycylglycine finds applications in pharmaceutical research and drug development. It can be used as a starting material for the synthesis of potential drug candidates or as a reference standard in analytical testing.

Current Status of Amino Acids: Amino acids play a crucial role in various sectors, including pharmaceuticals, peptide synthesis, and biochemistry. They are fundamental units of proteins and have diverse functions in the human body. Glycine, in particular, is one of the most abundant amino acids and has applications in various industries.

Conclusion: Boc-Glycylglycine (Boc-Gly-Gly-OH), derived from the coupling of Boc-Glycine and glycine, is an important compound in the chemical industry. Its production involves the protection and coupling of glycine, followed by deprotection to obtain Boc-Glycylglycine. The market demand for Boc-Glycylglycine is driven by its applications in peptide synthesis and pharmaceutical research. Amino acids, including glycine, continue to be essential components in various industries, contributing to advancements in chemical applications and biomedical research.

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