Synonyms
N-(tert-Butoxycarbonyl)glycin
Glycine, N-[(1,1-dimethylethoxy)carbonyl]-
Boc-glycine
N-Boc-protected glycine
n-boc-glycine
boc-gly
N-(tert-butoxycarbonyl)glycine
Boc-Gly-OH
MFCD00002690
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}glycine
N-Boc-L-glycine
2-((tert-Butoxycarbonyl)amino)acetic acid
({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)acetic acid
Glycine, N-carboxy-, N-tert-butyl ester
N-Boc glycine
EINECS 224-864-5
Product Description
Introduction:
BOC-Glycine is a widely used amino acid protecting agent in peptide synthesis. As an essential tool in
the field of peptide chemistry, BOC-Glycine plays a crucial role in protecting amino groups during the
assembly of peptide chains. Known for its reliability and versatility, BOC-Glycine has gained
significant popularity among chemists and researchers engaged in peptide synthesis.
Product Features:
High Purity: BOC-Glycine is meticulously synthesized to ensure the highest level of purity, surpassing
industry standards. Its exceptional purity guarantees minimal impurities, ensuring superior quality
results and the synthesis of high-quality peptides.
Effective Amine Protection: BOC-Glycine serves as an efficient protective group for amino groups,
preventing undesired side reactions during peptide synthesis. By selectively protecting the amino group,
it enables controlled and precise incorporation of amino acids into the growing peptide chain.
Compatibility with Various Synthesis Methods: BOC-Glycine exhibits excellent compatibility with a wide
range of peptide synthesis methods, including both solution-phase and solid-phase synthesis. Its
versatility allows chemists to employ diverse strategies in peptide assembly.
Applications:
Peptide Synthesis: BOC-Glycine plays a fundamental role in solid-phase peptide synthesis (SPPS), the
most widely used method for peptide assembly. As an amino acid protecting agent, it facilitates the
stepwise addition of amino acids, preserving the integrity and controlled growth of the peptide
chain.
Drug Development: BOC-Glycine finds extensive application in the pharmaceutical industry for the
synthesis of peptide-based drugs and drug candidates. It enables the incorporation of glycine residues
into peptides, contributing to the development of therapeutics targeting specific biological pathways or
receptors.
Peptide Modifications: BOC-Glycine is employed in peptide modification strategies, such as introducing
functional groups or attaching tags to peptides. These modifications can enhance peptide stability,
solubility, or target specificity, expanding their applications in drug discovery, molecular biology,
and bioconjugation studies.
Market Outlook:
The demand for BOC-Glycine is steadily growing within the peptide synthesis market due to its reliable
performance and compatibility with various synthesis methods. Pharmaceutical companies, academic
research institutions, and contract manufacturing organizations (CMOs) rely on BOC-Glycine for their
peptide synthesis projects. With the increasing interest in peptide-based drugs, medicinal chemistry,
and peptide modifications, there is a growing market for high-quality amino acid protecting
agents.
Conclusion:
BOC-Glycine stands as a versatile amino acid protecting agent in peptide synthesis. Its high purity,
effective amine protection, and compatibility with diverse synthesis methods make it an indispensable
tool for chemists and researchers involved in peptide-based studies. With its wide range of applications
in peptide synthesis, drug development, and peptide modifications, BOC-Glycine continues to drive
advancements in drug discovery, molecular biology, and the development of innovative therapeutic
strategies.
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