BOC-ON
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years；In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names BOC-ON
Structure
CAS　No. 58632-95-4 Boiling Point (℃) 324.1±25.0 °C at 760 mmHg
Molecular Weight 246.262 Melting Point (℃) 85-88 °C(lit.)
Density 1.1±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C13H14N2O3 Flash Point (℃) 149.8±23.2 °C
Solubility insoluble Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description DL-Lysine (Lysine) is an α-amino acid that is used in the biosynthesis of proteins.
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.
Synonyms
(2Z)-{[(tert-Butoxycarbonyl)oxy]imino}(phenyl)acetonitrile
Benzeneacetonitrile, α-[[[(1,1-dimethylethoxy)carbonyl]oxy]imino]-, (αZ)-
2-Butoxycarbonyloximino-2-phenylacetonitrile
(2Z)-[({[(2-Methyl-2-propanyl)oxy]carbonyl}oxy)imino](phenyl)acetonitrile
BOC-ON 25GR
Benzeneacetonitrile, α-((((1,1-dimethylethoxy)carbonyl)oxy)imino)-
EINECS 261-370-9
BOC-ON 5GR
MFCD00001863
BOC-ON
Product Description
BOC-ON, also known as Boc-anhydride or N-tert-butoxycarbonyl imide, is a widely used amino acid protecting reagent in the production of peptides and other biologically active compounds. It is a white to off-white crystalline powder with a molecular weight of 191.24 g/mol and a melting point of 19-21°C.

BOC-ON is commonly used in solid-phase peptide synthesis as a coupling agent, where it reacts with the amine group of the amino acid to form a stable amide bond. It also protects the amino group of the amino acid, preventing unwanted reactions during peptide synthesis. BOC-ON is compatible with a variety of amino acids and is easy to handle and store, making it a popular choice for peptide synthesis.

In addition to its use in peptide synthesis, BOC-ON is also used in the production of other biologically active compounds, including pharmaceuticals and agrochemicals. Its stability and reactivity make it a versatile reagent in the field of organic chemistry.

The global market for BOC-ON is expected to grow in the coming years due to the increasing demand for peptides and other biologically active compounds. The growth of the pharmaceutical and biotechnology industries is also expected to drive demand for BOC-ON, as it is an essential reagent in the production of many pharmaceuticals and other biologically active compounds.

Overall, BOC-ON is an important amino acid protecting reagent with a wide range of applications in the production of peptides and other biologically active compounds. Its versatility and compatibility with a variety of amino acids make it a popular choice in the field of organic chemistry, and its growing demand in the pharmaceutical and biotechnology industries is expected to drive market growth in the coming years.

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