BOC-L-Tyrosine Methyl Ester
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names Boc-L-Tyrosine methyl ester
Structure
CAS No. 4326-36-7 Boiling Point (℃) 452.7±40.0 °C at 760 mmHg
Molecular Weight 295.331 Melting Point (℃) 100-104 °C(lit.)
Density 1.2±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C15H21NO5 Flash Point (℃) 227.6±27.3 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description Boc-L-Tyrosine methyl ester is a tyrosine derivative[1].
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
Synonyms
Methyl N-(tert-butoxycarbonyl)-L-tyrosinate
MFCD00191181
N-Boc-L-tyrosine Methyl Ester
N-t-butyloxycarbonyl-S-tyrosine methyl ester
N-(tert-Butoxycarbonyl)-L-tyrosine Methyl Ester
Boc-Tyr-Ome
Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
Methyl N-{[(2-methyl-2-propanyl)oxy]carbonyl}tyrosinate
Boc-L-Tyrosinemethylester
Boc-L-Tyrosine Methyl Ester
Boc-L-tyrosine methylester
Product Description
Introduction: BOC-L-Tyrosine methyl ester is a vital amino acid protecting agent widely utilized in peptide synthesis. As an essential component of the peptide chemist's toolkit, BOC-L-Tyrosine methyl ester plays a critical role in protecting amino groups during the construction of peptide chains. Renowned for its versatility and reliability, BOC-L-Tyrosine methyl ester has become a preferred choice among chemists and researchers engaged in peptide synthesis.

Product Features: High Purity: BOC-L-Tyrosine methyl ester is carefully synthesized to ensure exceptional purity, surpassing industry standards. Its high purity guarantees minimal impurities, ensuring the synthesis of high-quality peptides and reliable results.

Effective Amine Protection: BOC-L-Tyrosine methyl ester serves as an efficient protective group for amino groups, preventing undesired side reactions during peptide synthesis. By selectively safeguarding the amino group, it facilitates the controlled and precise incorporation of amino acids into the growing peptide chain.

Compatibility with Diverse Synthesis Methods: BOC-L-Tyrosine methyl ester exhibits excellent compatibility with a wide range of peptide synthesis methods, including both solution-phase and solid-phase synthesis. Its versatility allows chemists to employ various strategies for efficient peptide assembly.

Applications: Peptide Synthesis: BOC-L-Tyrosine methyl ester plays a crucial role in solid-phase peptide synthesis (SPPS), the primary method for efficient peptide assembly. As an amino acid protecting agent, it facilitates the stepwise addition of amino acids, ensuring the proper growth and preservation of the peptide chain's integrity.

Drug Development: BOC-L-Tyrosine methyl ester finds extensive application in the pharmaceutical industry for the synthesis of peptide-based drugs and drug candidates. It enables the incorporation of tyrosine residues into peptides, facilitating the development of therapeutics targeting specific biological pathways or receptors.

Peptide Modifications: BOC-L-Tyrosine methyl ester is employed in peptide modification strategies, such as introducing functional groups or attaching tags to peptides. These modifications can enhance peptide stability, solubility, or target specificity, expanding their applications in drug discovery, molecular biology, and bioconjugation studies.

Market Outlook: The demand for BOC-L-Tyrosine methyl ester is steadily growing within the peptide synthesis market due to its reliable performance and compatibility with diverse synthesis methods. Pharmaceutical companies, academic research institutions, and contract manufacturing organizations (CMOs) rely on BOC-L-Tyrosine methyl ester for their peptide synthesis projects. With the increasing interest in peptide-based drugs, medicinal chemistry, and peptide modifications, there is a growing market for high-quality amino acid protecting agents.

Conclusion: BOC-L-Tyrosine methyl ester stands as a versatile amino acid protecting agent in peptide synthesis. Its high purity, effective amine protection, and compatibility with various synthesis methods make it an indispensable tool for chemists and researchers involved in peptide-based studies. With its wide range of applications in peptide synthesis, drug development, and peptide modifications, BOC-L-Tyrosine methyl ester continues to drive advancements in drug discovery, molecular biology, and the development of innovative therapeutic strategies.

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