BOC-L-Tyrosine Ethyl Ester
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names BOC-L-tyrosine ethyl ester
Structure
CAS No. 72594-77-5 Boiling Point (℃) 463.786ºC at 760 mmHg
Molecular Weight 309.358 Melting Point (℃) N/A
Density 1.15g/cm3 Vapor Specific Gravity N/A
Molecular Formula C16H23NO5 Flash Point (℃) N/A
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description DL-Lysine (Lysine) is an α-amino acid that is used in the biosynthesis of proteins.
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.
Synonyms
(S)-2-tert-butoxycarbonylamino-3-(4-hydroxyphenyl)propionic acid ethyl ester
Boc-L-Tyr-OEt
Boc-L-Tyrosine ethyl ester
(S)-Ethyl 2-((tert-butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propanoate
N-(tert-butoxycarbonyl)-L-tyrosine ethyl ester
Boc-Tyr-OEt
t-butoxycarbonyl-L-tyrosine ethyl ester
N-Boc-L-tyrosine ethyl ester
Dach platinum dinitrate
Product Description
Introduction: BOC-L-Tyrosine Ethyl Ester is a trusted amino acid protecting agent extensively employed in peptide synthesis. Derived from tyrosine, BOC-L-Tyrosine Ethyl Ester plays a pivotal role in safeguarding amino groups during the assembly of peptide chains. Known for its exceptional quality and reliability, BOC-L-Tyrosine Ethyl Ester has gained prominence among chemists and researchers involved in peptide synthesis.

Product Features: Superior Quality: BOC-L-Tyrosine Ethyl Ester is meticulously synthesized to ensure unmatched purity, surpassing industry standards. Its exceptional quality guarantees minimal impurities, ensuring optimal results and the synthesis of high-quality peptides.

Effective Amine Protection: BOC-L-Tyrosine Ethyl Ester acts as an efficient shield for amino groups, preventing undesired side reactions during peptide synthesis. By selectively protecting the amino group, it enables precise and controlled incorporation of amino acids into the growing peptide chain.

Enhanced Solubility: BOC-L-Tyrosine Ethyl Ester exhibits improved solubility properties, allowing for easy dissolution in common solvents used in peptide synthesis. This characteristic enhances its compatibility with various reaction conditions and facilitates efficient peptide assembly.

Applications: Peptide Synthesis: BOC-L-Tyrosine Ethyl Ester is an indispensable component in solid-phase peptide synthesis (SPPS), the preferred method for efficient peptide assembly. Its role as an amino acid protecting agent enables the stepwise addition of amino acids, preserving the integrity and controlled growth of the peptide chain.

Pharmaceutical Research: BOC-L-Tyrosine Ethyl Ester plays a significant role in the development of peptide-based therapeutics and drug discovery. Its usage enables the creation of diverse peptide libraries, allowing researchers to explore structure-activity relationships and identify potential drug candidates.

Biochemical Studies: BOC-L-Tyrosine Ethyl Ester finds extensive application in various biochemical studies, including enzymatic assays, receptor-ligand interactions, and peptide modifications. Its ability to protect the amino group allows for controlled functionalization of peptides, facilitating investigations into biological processes and molecular recognition.

Market Outlook: The demand for BOC-L-Tyrosine Ethyl Ester is experiencing steady growth within the peptide synthesis market due to its reliable performance and compatibility with various synthesis methods. Pharmaceutical companies, academic research institutions, and contract manufacturing organizations (CMOs) heavily rely on BOC-L-Tyrosine Ethyl Ester for their peptide synthesis projects. With the increasing interest in peptide-based therapeutics and biochemical research, there is a growing market for high-quality amino acid protecting agents.

Conclusion: BOC-L-Tyrosine Ethyl Ester stands as a trusted amino acid protecting agent in peptide synthesis. Its superior quality, effective amine protection, and enhanced solubility make it an essential tool for chemists and researchers involved in peptide-based studies. With its wide range of applications in peptide synthesis, pharmaceutical research, and biochemical studies, BOC-L-Tyrosine Ethyl Ester continues to drive advancements in therapeutic development and our understanding of complex biochemical processes.

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