BOC-L-Serine
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names BOC-L-Serine
Structure
CAS No. 3262-72-4 Boiling Point (℃) 385.1±37.0 °C at 760 mmHg
Molecular Weight 205.208 Melting Point (℃) 91 °C (dec.)(lit.)
Density 1.2±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C8H15NO5 Flash Point (℃) 186.7±26.5 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description (S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxypropanoic acid is a serine derivative[1].
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
Synonyms
Boc-L-serine
L-Serine-d3-N-t-BOC
(S)-2-(tert-Butoxycarbonylamino)-3-hydroxypropanoic acid
BOC-L-SERINE extrapure
t-butyloxycarbonyl-L-serine
N-Boc-L-serine
MFCD00037243
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-serine
L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-
BOC-L-PROLINOL LIQUID
Boc-Ser-OH
BOC-SERINE-OH
EINECS 221-867-3
BOC-L-SER-OH
(S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxypropanoic acid
BOC-L-SER
N-(tert-Butoxycarbonyl)-L-serine,Boc-L-serine
BOC-SERINE
N-(tert-Butoxycarbonyl)-L-serine
Product Description
BOC-L-serine is a derivative of the amino acid L-serine and is widely used as a protecting group in peptide synthesis. The BOC group is introduced to protect the amino group of serine, allowing for selective deprotection at a later stage in the synthesis.

Production of BOC-L-serine involves the reaction of L-serine with BOC-anhydride in the presence of a base such as triethylamine. The resulting BOC-L-serine can then be purified by methods such as crystallization or chromatography.

BOC-L-serine is commonly used in the production of peptides and proteins for pharmaceutical and biotech applications. The use of protected amino acids in peptide synthesis allows for greater control over the reaction and reduces the likelihood of unwanted side reactions.

The market for BOC-L-serine is expected to grow in line with the increasing demand for peptides and protein therapeutics. The use of protected amino acids in peptide synthesis is becoming more widespread as the need for more specific and effective drugs increases.

Overall, BOC-L-serine is an important building block in peptide synthesis and its market is expected to continue to grow alongside the biotech industry.

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