1-O-tert-butyl 2-O-methyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate
MFCD06809720
1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S)-
2-Methyl 1-(2-methyl-2-propanyl) (2S)-5-oxo-1,2-pyrrolidinedicarboxylate
Boc-pGlu-OMe
Methyl (2S)-1-(tert-butoxycarbonyl)py
Boc-Pyr-OMe
Methyl Boc-L-Pyroglutamate
N-Boc-L-pyroglutamic acid methyl ester
Methyl (S)-N-(tert-butoxycarbonyl)pyroglutamate
Boc-L-Pyroglutamic acid methylester
Methyl (S)-Boc-5-pyrrolidone-2-carboxylate
Boc-L-Pyroglutamic acid methyl ester
(S)-1-tert-Butyl 2-methyl 5-oxopyrrolidine-1,2-dicarboxylate
1-tert-butyl 2-methyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate

BOC-L-Pyroglutamic Acid Methyl Ester is a vital amino acid protecting agent widely used in peptide synthesis. With its excellent protecting properties and compatibility with peptide assembly techniques, BOC-L-Pyroglutamic Acid Methyl Ester enables the synthesis of peptides containing pyroglutamic acid residues. Its high purity, reliability, and versatility make it an essential tool for chemists and researchers involved in peptide synthesis projects.

Product Features: High Purity: BOC-L-Pyroglutamic Acid Methyl Ester is manufactured with meticulous attention to purity, ensuring minimal impurities. Its superior quality guarantees the synthesis of peptides with excellent purity and structural integrity.

Effective Protecting Group: BOC-L-Pyroglutamic Acid Methyl Ester acts as a reliable protecting group for the glutamic acid residue, preventing unwanted reactions during peptide chain elongation. It selectively shields the carboxyl group, allowing controlled incorporation of pyroglutamic acid into peptides.

Enhanced Stability: Peptides containing pyroglutamic acid residues exhibit improved stability due to the cyclization of the N-terminal glutamic acid residue. BOC-L-Pyroglutamic Acid Methyl Ester facilitates this cyclization process, resulting in peptides with enhanced resistance to enzymatic degradation and improved bioavailability.

Applications: Peptide Therapeutics: BOC-L-Pyroglutamic Acid Methyl Ester plays a crucial role in the synthesis of peptide-based therapeutics. The incorporation of pyroglutamic acid residues in peptides can confer enhanced stability, resistance to enzymatic degradation, and improved cell penetration properties. Peptide drugs containing pyroglutamic acid residues have shown promise in various therapeutic areas, including neurodegenerative diseases and metabolic disorders.

Neurobiology Research: BOC-L-Pyroglutamic Acid Methyl Ester is widely used in neurobiology research to synthesize peptides involved in the study of neuropeptides and neurotransmitters. The presence of pyroglutamic acid residues in these peptides is crucial for their proper folding, stability, and receptor-binding properties. Such peptides are valuable tools for investigating the molecular mechanisms underlying brain function and developing therapies for neurological disorders.

Cosmetic and Skincare Formulations: BOC-L-Pyroglutamic Acid Methyl Ester finds application in the formulation of cosmetic and skincare products. Pyroglutamic acid derivatives are known for their hydrating, anti-aging, and skin-soothing properties. Incorporating pyroglutamic acid residues into peptides allows for the development of innovative cosmetic formulations targeting skin health and rejuvenation.

Market Outlook: The demand for BOC-L-Pyroglutamic Acid Methyl Ester is steadily increasing due to its significance in peptide synthesis and its diverse applications in therapeutic development, neurobiology research, and skincare formulations. Pharmaceutical companies, academic institutions, and cosmetic manufacturers rely on BOC-L-Pyroglutamic Acid Methyl Ester for the synthesis of peptides with enhanced stability and unique functional properties. As the demand for peptide-based therapeutics and advanced skincare products continues to grow, the market for amino acid protecting agents such as BOC-L-Pyroglutamic Acid Methyl Ester is expected to expand.

Conclusion: BOC-L-Pyroglutamic Acid Methyl Ester is a versatile and reliable amino acid protecting agent used in peptide synthesis. Its high purity, effective protection of the carboxyl group, and compatibility with various synthesis techniques enable the incorporation of pyroglutamic acid residues into peptides, leading to enhanced stability and functional properties. The applications of BOC