Synonyms
N-Boc-L-leucine hydrate
(E)-N-{Hydroxy[(2-methyl-2-propanyl)oxy]methylene}-L-leucine
(S)-2-((tert-Butoxycarbonyl)amino)-4-methylpentanoic acid
MFCD00066067
L-LEUCINE-N-T-BOC:H2O
L-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-
BOC-LEU
boc-leu-oh.h20
EINECS 236-073-2
N-tert-butoxycarbonyl-L-leucine
BOC-L-LEUCINE-OH
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-leucine
N-tert-butyloxycarbonyl-L-leucine
BOC-L-Leucine
Product Description
Introduction:
BOC-L-Leucine is a versatile amino acid protecting agent widely used in peptide synthesis. Derived from
leucine, BOC-L-Leucine plays a crucial role in protecting amino groups during the assembly of peptide
chains. Renowned for its exceptional quality and reliability, BOC-L-Leucine has become a preferred
choice among chemists and researchers involved in peptide synthesis.
Product Features:
High Purity: BOC-L-Leucine is meticulously synthesized to ensure the highest level of purity, surpassing
industry standards. Its exceptional purity guarantees minimal impurities, ensuring superior quality
results and the synthesis of high-quality peptides.
Effective Amine Protection: BOC-L-Leucine acts as an efficient shield for amino groups, preventing
undesired side reactions during peptide synthesis. By selectively protecting the amino group, it enables
controlled and precise incorporation of amino acids into the growing peptide chain.
Compatibility with Various Synthesis Methods: BOC-L-Leucine exhibits excellent compatibility with a wide
range of peptide synthesis methods, including both solution-phase and solid-phase synthesis. Its
versatility allows chemists to utilize diverse strategies in peptide assembly.
Applications:
Peptide Synthesis: BOC-L-Leucine is an essential component in solid-phase peptide synthesis (SPPS), the
most widely used method for efficient peptide assembly. Its role as an amino acid protecting agent
enables the stepwise addition of amino acids, preserving the integrity and controlled growth of the
peptide chain.
Drug Development: BOC-L-Leucine finds significant application in the pharmaceutical industry for the
synthesis of peptide-based drugs and drug candidates. It enables the incorporation of leucine residues
into peptides, allowing for the development of therapeutics targeting specific biological pathways or
receptors.
Peptide Modifications: BOC-L-Leucine is employed in peptide modification strategies, such as the
introduction of functional groups or attachment of tags to peptides. These modifications can enhance
peptide stability, solubility, or target specificity, expanding their applications in drug discovery,
molecular biology, and bioconjugation studies.
Market Outlook:
The demand for BOC-L-Leucine is experiencing steady growth within the peptide synthesis market due to
its reliable performance and compatibility with various synthesis methods. Pharmaceutical companies,
academic research institutions, and contract manufacturing organizations (CMOs) heavily rely on
BOC-L-Leucine for their peptide synthesis projects. With the increasing interest in peptide-based drugs,
medicinal chemistry, and peptide modifications, there is a growing market for high-quality amino acid
protecting agents.
Conclusion:
BOC-L-Leucine stands as a versatile amino acid protecting agent in peptide synthesis. Its high purity,
effective amine protection, and compatibility with various synthesis methods make it an indispensable
tool for chemists and researchers involved in peptide-based studies. With its wide range of applications
in peptide synthesis, drug development, and peptide modifications, BOC-L-Leucine continues to drive
advancements in drug discovery, molecular biology, and the development of innovative therapeutic
strategies.
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