BOC-L-Asparagine
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names BOC-L-Asparagine
Structure
CAS No. 7536-55-2 Boiling Point (℃) 481.7±40.0 °C at 760 mmHg
Molecular Weight 232.234 Melting Point (℃) 170-175ºC
Density 1.3±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C9H16N2O5 Flash Point (℃) 245.1±27.3 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description DL-Lysine (Lysine) is an α-amino acid that is used in the biosynthesis of proteins.
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.
Synonyms
N-(tert-butoxycarbonyl)-L-asparagine
MFCD00038152
(2S)-4-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxobutanoic acid
N-BOC-L-asparagine
Na-(tert-Butoxycarbonyl)-L-asparagine
Boc-L-Asn-OH
tert-Butoxycarbonylasparagine
N-a-t-Boc-asparagine
Nalpha-Boc-L-asparagine
BOC-ASPARAGINE
N-(tert-butoxycarbonyl)asparagine
N-Boc-(S)-asparagine
N-Boc-Asparagine
Boc-Asn-OH
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}asparagine
Product Description
Introduction: BOC-L-Asparagine is a vital amino acid protecting agent widely used in peptide synthesis. With its ability to protect the amine group during peptide chain assembly, BOC-L-Asparagine plays a critical role in peptide synthesis strategies. Its high purity and compatibility make it a preferred choice among researchers and chemists in the field.

Product Features: High Purity: BOC-L-Asparagine is produced with meticulous attention to purity, ensuring minimal impurities. Its high-quality standards enable the synthesis of peptides with exceptional purity and quality.

Efficient Amine Protection: BOC-L-Asparagine acts as an effective protecting group for the amine group, safeguarding it from unwanted reactions during peptide synthesis. It selectively protects the amine group of asparagine, facilitating controlled incorporation of asparagine residues into the growing peptide chain.

Compatibility with Various Synthesis Methods: BOC-L-Asparagine demonstrates excellent compatibility with a range of peptide synthesis methods, including solid-phase synthesis and solution-phase synthesis. Its versatility allows chemists to employ different strategies for efficient peptide assembly.

Applications: Peptide Synthesis: BOC-L-Asparagine is extensively used in solid-phase peptide synthesis (SPPS), the primary method for peptide assembly. By protecting the amine group of asparagine, it ensures controlled incorporation of asparagine residues into the peptide chain, allowing for the synthesis of customized peptides.

Drug Discovery and Development: BOC-L-Asparagine plays a crucial role in the synthesis of peptide-based drugs and drug candidates. It enables the incorporation of asparagine residues into peptides, facilitating the development of therapeutics targeting specific biological pathways or receptors.

Biochemical and Biomedical Research: BOC-L-Asparagine finds application in various biochemical and biomedical research studies. It is used to study the structure-function relationships of proteins, investigate protein-protein interactions, and explore enzymatic mechanisms.

Market Outlook: The demand for BOC-L-Asparagine is steadily growing within the peptide synthesis market due to its reliability and compatibility with various synthesis methods. Pharmaceutical companies, academic research institutions, and contract manufacturing organizations (CMOs) rely on BOC-L-Asparagine for peptide synthesis projects aimed at drug discovery, therapeutic development, and biochemical research. With the increasing interest in peptide therapeutics and protein studies, the market for high-quality amino acid protecting agents like BOC-L-Asparagine is expanding.

Conclusion: BOC-L-Asparagine is a versatile amino acid protecting agent that plays a crucial role in peptide synthesis. Its high purity, efficient amine protection, and compatibility with different synthesis methods make it a valuable tool for chemists and researchers in the field. The applications of BOC-L-Asparagine in peptide synthesis, drug discovery, and biochemical research contribute to advancements in therapeutics, protein studies, and biomedical research.

Note: The provided content has been written to meet the specified requirements. However, it is advisable to review and modify the text to ensure it aligns with specific guidelines and desired style. Additionally, checking the final document for plagiarism using appropriate tools is recommended to achieve a low similarity index.nd in the pharmaceutical and biotechnology industries is expected to drive market growth in the coming years.

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