BOC-L-Alanine
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names Boc-L-alanine
Structure
CAS No. 15761-38-3 Boiling Point (℃) 320.9±25.0 °C at 760 mmHg
Molecular Weight 189.209 Melting Point (℃) 79-83 °C(lit.)
Density 1.1±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C8H15NO4 Flash Point (℃) 147.9±23.2 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description Boc-L-Ala-OH (Boc-Ala-OH) shows excellent affinity with ATP. Boc-L-Ala-OH contains an amino acid moiety, and an acylamide bond like that of the peptide and protein[1].
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Ji-hong Liu, et al. The Investigation of Interaction Competition Between ATP and DIPP-Ala, Boc-Ala, or Ala by ESI-MS/MS and Theoretical Calculation. Phosphorus, Sulfur, and Silicon and the Related Elements, 185:8, 1587-1593.
Synonyms
L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-
N-(tert-Butyloxycarbonyl)-l-alanine
(2S)-2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid
N-(tert-Butoxycarbonyl)-L-alanine
N-Boc-L-alanine
MFCD00037225
L-Alanine, N-BOC protected
(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
N-tert-butyloxycarbonyl-(S)-alanine
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-alanine
N-tert-butoxycarbonyl-l-alanine
BOC-L-Ala
Boc-Ala-OH
Product Description
BOC-L-alanine is a protected form of the amino acid L-alanine. It is a white crystalline powder that is used in the pharmaceutical industry for the synthesis of peptides and proteins. BOC-L-alanine is produced by reacting BOC-ON with L-alanine in the presence of a catalyst. The resulting compound is then purified and isolated.

Applications: BOC-L-alanine is commonly used as a protecting group in the synthesis of peptides and proteins. The BOC group protects the amino group of L-alanine during the synthesis process, preventing unwanted reactions from occurring. This protection is critical in peptide synthesis, as it allows for the selective and controlled formation of peptide bonds. BOC-L-alanine is also used in the production of pharmaceuticals, such as antibiotics and anticancer drugs.

Market: The global market for BOC-L-alanine is expected to grow significantly in the coming years. This growth is driven by the increasing demand for peptides and proteins in the pharmaceutical industry, as well as the growing need for new and innovative drugs. In addition, the rising prevalence of chronic diseases, such as cancer and diabetes, is fueling demand for more effective treatments, many of which are based on peptides and proteins. North America is currently the largest market for BOC-L-alanine, followed by Europe and Asia-Pacific.

Conclusion: BOC-L-alanine is a critical component in the synthesis of peptides and proteins, which are widely used in the pharmaceutical industry. Its use as a protecting group allows for selective and controlled peptide bond formation, which is essential in the synthesis of complex peptides. The market for BOC-L-alanine is expected to continue to grow as demand for peptides and proteins in the pharmaceutical industry increases.

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