Synonyms
Benzeneacetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-
[(tert-Butoxycarbonyl)amino](phenyl)acetic acid
MFCD00971063
({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)(phenyl)acetic acid
N-Boc-DL-phenylglycine
TERT-BUTOXYCARBONYLAMINO-PHENYL-ACETIC ACID
BOC-DL-(PHENYL)GLY-OH
Product Description
BOC-DL-Phenylglycine is a versatile amino acid protecting agent widely used in peptide synthesis.
Derived from phenylglycine, BOC-DL-Phenylglycine plays a crucial role in protecting amino groups during
the assembly of peptide chains. Known for its exceptional quality and reliability, BOC-DL-Phenylglycine
has become a preferred choice among chemists and researchers involved in peptide synthesis.
Product Features:
Superior Purity: BOC-DL-Phenylglycine is meticulously synthesized to ensure the highest level of purity,
surpassing industry standards. Its exceptional purity guarantees minimal impurities, ensuring superior
quality results and the synthesis of high-quality peptides.
Effective Amine Protection: BOC-DL-Phenylglycine acts as an efficient shield for amino groups,
preventing undesired side reactions during peptide synthesis. By selectively protecting the amino group,
it enables controlled and precise incorporation of amino acids into the growing peptide chain.
Enhanced Solubility: BOC-DL-Phenylglycine exhibits improved solubility properties, allowing for easy
dissolution in common solvents used in peptide synthesis. This characteristic enhances its compatibility
with various reaction conditions and facilitates efficient peptide assembly.
Applications:
Peptide Synthesis: BOC-DL-Phenylglycine is an essential component in solid-phase peptide synthesis
(SPPS), the most widely used method for efficient peptide assembly. Its role as an amino acid protecting
agent enables the stepwise addition of amino acids, preserving the integrity and controlled growth of
the peptide chain.
Medicinal Chemistry: BOC-DL-Phenylglycine finds significant application in medicinal chemistry for the
synthesis of peptide-based drugs and drug candidates. Its utilization allows for the creation of diverse
peptide libraries, facilitating structure-activity relationship studies and the identification of
potential therapeutic leads.
Peptide Mimetics: BOC-DL-Phenylglycine is employed in the design and synthesis of peptide mimetics,
which are non-peptide compounds that mimic the structural and functional properties of peptides. These
peptide mimetics offer advantages in drug discovery, including improved stability, bioavailability, and
target selectivity.
Market Outlook:
The demand for BOC-DL-Phenylglycine is experiencing steady growth within the peptide synthesis market
due to its reliable performance and compatibility with various synthesis methods. Pharmaceutical
companies, academic research institutions, and contract manufacturing organizations (CMOs) heavily rely
on BOC-DL-Phenylglycine for their peptide synthesis projects. With the increasing interest in
peptide-based drugs, medicinal chemistry, and peptide mimetics, there is a growing market for
high-quality amino acid protecting agents.
Conclusion:
BOC-DL-Phenylglycine stands as a versatile amino acid protecting agent in peptide synthesis. Its
superior purity, effective amine protection, and enhanced solubility make it an indispensable tool for
chemists and researchers involved in peptide-based studies. With its wide range of applications in
peptide synthesis, medicinal chemistry, and peptide mimetics, BOC-DL-Phenylglycine continues to drive
advancements in drug discovery and the development of innovative therapeutic strategies.
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