Synonyms
N-BOC-L-Tryptophane
Nalpha-Boc-D-tryptophan
D-N-Boc-trytophan
N-Boc-R-tryptophan
Boc-D-Trp-OH
BOC-D-TRYPTOPHANE
MFCD00037944
N-(tert-Butoxycarbonyl)-D-tryptophan
EINECS 226-042-1
Boc-D-tryptophan
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-tryptophan
Nalpha-Boc-D-Tryptophane
Boc-D-Trp
N-Boc-D-tryptophan
D-Tryptophan, N-[(1,1-dimethylethoxy)carbonyl]-
tert-butyloxycarbonyl-D-tryptophan
Product Description
Introduction:
BOC-D-Tryptophan is a vital amino acid protecting agent extensively used in peptide synthesis. Derived
from tryptophan, BOC-D-Tryptophan plays a critical role in safeguarding amino groups during the assembly
of peptide chains. Known for its exceptional quality and reliability, BOC-D-Tryptophan has become the
preferred choice among chemists and researchers involved in peptide synthesis.
Product Features:
High Purity: BOC-D-Tryptophan is meticulously synthesized to ensure the highest level of purity,
surpassing industry standards. Its exceptional purity guarantees minimal impurities, ensuring superior
quality results and the synthesis of high-quality peptides.
Effective Amine Protection: BOC-D-Tryptophan serves as a highly efficient protecting group for amino
groups, preventing undesired side reactions during peptide synthesis. By selectively protecting the
amino group, it enables controlled and precise incorporation of amino acids into the growing peptide
chain.
Compatibility with Various Synthesis Methods: BOC-D-Tryptophan exhibits excellent compatibility with a
wide range of peptide synthesis methods, including both solution-phase and solid-phase synthesis. Its
versatility allows chemists to employ diverse strategies in peptide assembly.
Applications:
Peptide Synthesis: BOC-D-Tryptophan plays a pivotal role in solid-phase peptide synthesis (SPPS), the
most widely used method for efficient peptide assembly. As an amino acid protecting agent, it
facilitates the stepwise addition of amino acids, preserving the integrity and controlled growth of the
peptide chain.
Drug Development: BOC-D-Tryptophan finds significant application in the pharmaceutical industry for the
synthesis of peptide-based drugs and drug candidates. It enables the incorporation of tryptophan
residues into peptides, facilitating the development of therapeutics targeting specific biological
pathways or receptors.
Peptide Modifications: BOC-D-Tryptophan is employed in peptide modification strategies, such as
introducing functional groups or attaching tags to peptides. These modifications can enhance peptide
stability, solubility, or target specificity, expanding their applications in drug discovery, molecular
biology, and bioconjugation studies.
Market Outlook:
The demand for BOC-D-Tryptophan is experiencing steady growth within the peptide synthesis market due to
its reliable performance and compatibility with various synthesis methods. Pharmaceutical companies,
academic research institutions, and contract manufacturing organizations (CMOs) heavily rely on
BOC-D-Tryptophan for their peptide synthesis projects. With the increasing interest in peptide-based
drugs, medicinal chemistry, and peptide modifications, there is a growing market for high-quality amino
acid protecting agents.
Conclusion:
BOC-D-Tryptophan serves as a key amino acid protecting agent in peptide synthesis. Its high purity,
effective amine protection, and compatibility with diverse synthesis methods make it an essential tool
for chemists and researchers involved in peptide-based studies. With its wide range of applications in
peptide synthesis, drug development, and peptide modifications, BOC-D-Tryptophan continues to drive
advancements in drug discovery, molecular biology, and the development of innovative therapeutic
strategies.
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