Synonyms
Boc-D-Phe-OH
(2R)-2-[(tert-butoxy)carbonylamino]-3-phenylpropanoic acid
N-(t-butyloxycarbonyl)-D-Phenylalanine
Boc-phenylalanine
BOC-D-PHE
Boc-L-Phenylalanine
(2S)-2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoic acid
N-Boc-D-phenylalanine
(S)-2-((tert-Butoxycarbonyl)amino)-3-phenylpropanoic acid
N-(tert-Butoxycarbonyl)-L-phenylalanine
boc-L-Phe
MFCD00063149
L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-
N-t-Butyloxycarbonyl-L-phenylalanine
N-(t-butoxycarbonyl)-D-phenylalanine
L-Phenylalanine, N-((1,1-dimethylethoxy)carbonyl)-
N-Boc-L-phenylalanine
Product Description
Introduction:
BOC-D-Phenylalanine is a vital amino acid protecting agent widely utilized in peptide synthesis. With
its ability to safeguard amino groups during peptide chain assembly, BOC-D-Phenylalanine plays a crucial
role in peptide synthesis strategies. Its versatility and reliability make it highly sought after by
researchers and chemists in the field.
Product Features:
Exceptional Purity: BOC-D-Phenylalanine is produced with meticulous attention to purity. Its
high-quality standards ensure minimal impurities, allowing for the synthesis of peptides with excellent
quality and purity.
Efficient Amine Protection: BOC-D-Phenylalanine acts as a highly effective protective group for amino
groups, preventing unwanted side reactions during peptide synthesis. It selectively shields the amino
group of phenylalanine, facilitating precise incorporation of phenylalanine residues into the growing
peptide chain.
Compatibility with Diverse Synthesis Methods: BOC-D-Phenylalanine demonstrates excellent compatibility
with various peptide synthesis methods, including both solution-phase and solid-phase synthesis. Its
versatility enables chemists to employ different strategies for efficient peptide assembly.
Applications:
Peptide Synthesis: BOC-D-Phenylalanine plays a pivotal role in solid-phase peptide synthesis (SPPS),
which is the primary method for peptide assembly. By protecting the amino group of phenylalanine, it
ensures controlled incorporation of phenylalanine residues into the peptide chain, allowing for the
synthesis of customized peptides.
Medicinal Chemistry: BOC-D-Phenylalanine is extensively utilized in the synthesis of peptide-based drugs
and drug candidates. It enables the incorporation of phenylalanine residues into peptides, facilitating
the development of therapeutics targeting specific biological pathways or receptors.
Protein Engineering: BOC-D-Phenylalanine finds application in protein engineering studies. By
incorporating BOC-D-Phenylalanine into specific positions within the protein sequence, researchers can
investigate the impact of phenylalanine mutations on protein structure, function, and stability.
Market Outlook:
The demand for BOC-D-Phenylalanine is growing steadily within the peptide synthesis market due to its
reliability and compatibility with various synthesis methods. Pharmaceutical companies, academic
research institutions, and contract manufacturing organizations (CMOs) rely on BOC-D-Phenylalanine for
peptide synthesis projects aimed at drug discovery and development. With the increasing interest in
peptide therapeutics and protein engineering, the market for high-quality amino acid protecting agents
like BOC-D-Phenylalanine is expanding.
Conclusion:
BOC-D-Phenylalanine is a versatile amino acid protecting agent that plays a crucial role in peptide
synthesis. Its exceptional purity, efficient amine protection, and compatibility with diverse synthesis
methods make it a valuable tool for chemists and researchers in the field. The applications of
BOC-D-Phenylalanine in peptide synthesis, medicinal chemistry, and protein engineering contribute to
advancements in drug development, therapeutic design, and protein structure-function studies.
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