BOC-D-Leucine
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
Free Quote
For samples, pricing, or more information, please call us at 0086-25-52397805 or mail to info@alchemist-chem.com or fill out the following form.
We will respond to you as soon as possible.

Tel: 0086-25-52397805

Email: info@alchemist-chem.com

General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names Boc-D-Leu-OH.H2O
Structure
CAS No. 16937-99-8 Boiling Point (℃) 356.0±25.0 °C at 760 mmHg
Molecular Weight 231.289 Melting Point (℃) 85-87ºC(lit.)
Density 1.1±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C11H21NO4 Flash Point (℃) 169.1±23.2 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description (tert-Butoxycarbonyl)-D-leucine is a leucine derivative[1].
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
Synonyms
MFCD00038294
BOC-D-Leucinemonohydrate
Boc-D-Leu-OH&BOC-D-LEU
N-BOC-D-Leucine.H2O
Boc-D-Leu-OH Hydrate
N-(tert-Butoxycarbonyl)-D-leucine
D-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-, hydrate (1:1)
BOC-D-LEUCINE-OH
N-T-BOC-D-LEUCINE
Boc-D-Leu-OH
N-(tert-Butoxycarbonyl)-D-leucine hydrate (1:1)
N-(tert-Butoxycarbonyl)-D-leucine Hydrate
BOC-D-LEU-OH2O
N-tert-butoxycarbonyl-D-leucine
n-boc-d-leucine
N-Boc-D-leucine Hydrate
D-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-
tert-butoxycarbonyl-D-leucine
N-(t-butyloxycarbonyl)-D-leucine
BOC-D-LEUCINE
Product Description
BOC-D-Leucine is a vital amino acid protecting agent widely employed in peptide synthesis. With its exceptional ability to protect the amine group during peptide chain assembly, BOC-D-Leucine plays a pivotal role in peptide synthesis strategies. Its high purity, reliability, and versatility make it a preferred choice among scientists and chemists in the field.

Product Features: High Purity: BOC-D-Leucine is manufactured with utmost care to ensure high purity, minimizing impurities. Its superior quality guarantees the synthesis of peptides with outstanding purity and integrity.

Efficient Amine Protection: BOC-D-Leucine serves as an effective safeguarding group for the amine group, preventing undesired reactions during peptide synthesis. It selectively shields the amine group of leucine, allowing controlled incorporation of leucine residues into the growing peptide chain.

Compatibility with Various Synthesis Methods: BOC-D-Leucine demonstrates remarkable compatibility with various peptide synthesis techniques, including solid-phase synthesis and solution-phase synthesis. Its versatility empowers chemists to employ different strategies for efficient peptide assembly.

Applications: Peptide Synthesis: BOC-D-Leucine is extensively utilized in solid-phase peptide synthesis (SPPS), the primary method for peptide construction. By protecting the amine group of leucine, it ensures precise integration of leucine residues into the peptide chain, facilitating the synthesis of customized peptides.

Drug Discovery and Development: BOC-D-Leucine plays a crucial role in synthesizing peptide-based drugs and drug candidates. It enables the incorporation of leucine residues into peptides, aiding the development of therapeutics targeting specific biological pathways or receptors.

Peptide Modification: BOC-D-Leucine is employed in peptide modification techniques, such as N-terminal labeling or side chain functionalization. By selectively shielding the amine group of leucine, it allows chemists to introduce desired modifications at specific sites within the peptide sequence.

Market Outlook: The demand for BOC-D-Leucine is steadily growing within the peptide synthesis market owing to its reliability and compatibility with various synthesis methods. Pharmaceutical companies, academic research institutions, and contract manufacturing organizations (CMOs) rely on BOC-D-Leucine for peptide synthesis projects aimed at drug discovery, therapeutic development, and biochemical research. With the increasing interest in peptide therapeutics and modified peptides, the market for high-quality amino acid protecting agents like BOC-D-Leucine is expanding.

Conclusion: BOC-D-Leucine is a versatile amino acid protecting agent that plays a pivotal role in peptide synthesis. Its high purity, efficient amine protection, and compatibility with different synthesis methods make it a valuable tool for chemists and researchers in the field. The applications of BOC-D-Leucine in peptide synthesis, drug discovery, and peptide modification contribute to advancements in therapeutics, peptide-based drugs, and biochemical research.

Note: The provided content has been written to meet the specified requirements. However, it is advisable to review and modify the text to ensure it aligns with specific guidelines and desired style. Additionally, checking the final document for plagiarism using appropriate tools is recommended to achieve a low similarity index.

Leave A Message
Leave A Message ×
If you are interested in our products and want to know more details,please leave a message here,we will reply you as soon as we can.