BOC-D-Aspartic Acid
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names Boc-D-Asp-OH
Structure
CAS No. 62396-48-9 Boiling Point (℃) 377.4±32.0 °C at 760 mmHg
Molecular Weight 233.219 Melting Point (℃) N/A
Density 1.3±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C9H15NO6 Flash Point (℃) 182.1±25.1 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description (tert-Butoxycarbonyl)-D-aspartic acid is an aspartic acid derivative[1].
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
Synonyms
N-(tert-Butoxycarbonyl)-D-aspartic Acid
tert-Butyloxycarbonyl-D-aspartic acid
Boc-D-Asparticacid
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-aspartic acid
N-Boc-D-aspartic Acid
N-tert-butoxycarbonyl-D-aspartic acid
Boc-D-Asp-OH
D-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-
MFCD00798618
N-Boc-D-Asp
Product Description
BOC-D-Aspartic Acid is a vital amino acid protecting agent widely used in peptide synthesis. With its exceptional ability to protect the amine group during peptide chain assembly, BOC-D-Aspartic Acid plays a crucial role in peptide synthesis strategies. Its high purity, reliability, and versatility make it a preferred choice among scientists and chemists in the field.

Product Features: High Purity: BOC-D-Aspartic Acid is produced with utmost care to ensure high purity, minimizing impurities. Its superior quality guarantees the synthesis of peptides with exceptional purity and integrity.

Effective Amine Protection: BOC-D-Aspartic Acid serves as a reliable safeguarding group for the amine group, preventing undesired reactions during peptide synthesis. It selectively protects the amine group of aspartic acid, allowing controlled incorporation of aspartic acid residues into the growing peptide chain.

Compatibility with Diverse Synthesis Methods: BOC-D-Aspartic Acid demonstrates excellent compatibility with various peptide synthesis techniques, including solid-phase synthesis and solution-phase synthesis. Its versatility empowers chemists to employ different strategies for efficient peptide assembly.

Applications: Peptide Synthesis: BOC-D-Aspartic Acid is extensively used in solid-phase peptide synthesis (SPPS), the primary method for peptide construction. By protecting the amine group of aspartic acid, it ensures precise integration of aspartic acid residues into the peptide chain, facilitating the synthesis of customized peptides.

Drug Discovery and Development: BOC-D-Aspartic Acid plays a vital role in synthesizing peptide-based drugs and drug candidates. It enables the incorporation of aspartic acid residues into peptides, facilitating the development of therapeutics targeting specific biological pathways or receptors.

Peptide Modification: BOC-D-Aspartic Acid is employed in peptide modification techniques, such as N-terminal labeling or side chain functionalization. By selectively protecting the amine group of aspartic acid, it allows chemists to introduce desired modifications at specific sites within the peptide sequence.

Market Outlook: The demand for BOC-D-Aspartic Acid is steadily growing within the peptide synthesis market due to its reliability and compatibility with various synthesis methods. Pharmaceutical companies, academic research institutions, and contract manufacturing organizations (CMOs) rely on BOC-D-Aspartic Acid for peptide synthesis projects aimed at drug discovery, therapeutic development, and biochemical research. With the increasing interest in peptide therapeutics and modified peptides, the market for high-quality amino acid protecting agents like BOC-D-Aspartic Acid is expanding.

Conclusion: BOC-D-Aspartic Acid is a versatile amino acid protecting agent that plays a crucial role in peptide synthesis. Its high purity, effective amine protection, and compatibility with different synthesis methods make it a valuable tool for chemists and researchers in the field. The applications of BOC-D-Aspartic Acid in peptide synthesis, drug discovery, and peptide modification contribute to advancements in therapeutics, peptide-based drugs, and biochemical research.

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