1,4-Diaminecyclohexane
Nanjing Finechem Holdings Co., LTD
Specifications
N/A
Packing & Storage
Packing
Storage Powder -20°C 3 years 4°C 2 years;In solvent -80°C 6 months, -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
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General Information
Chemical & Physical Properties
Safety Information
Synthetic Route
Biological Activity
Common Names 1,4-Cyclohexanediamine
Structure
CAS No. 3114-70-3 Boiling Point (℃) 199.4±8.0 °C at 760 mmHg
Molecular Weight 114.189 Melting Point (℃) N/A
Density 0.9±0.1 g/cm3 Vapor Specific Gravity N/A
Molecular Formula C6H14N2 Flash Point (℃) 80.0±0.0 °C
Solubility N/A Autoignition Temperature (℃) N/A
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+:Very toxic
Safety Phrases S1-S28-S45
RIDADR NONH for all modes of transport
WGK Germany  3
SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Use local exhaust or breathing protection. Fresh air, rest.
Skin Redness. Burning sensation. Itching. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes Redness. Pain. Wear safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion Abdominal pain. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention.
Description DL-Lysine (Lysine) is an α-amino acid that is used in the biosynthesis of proteins.
Target Km: 100-400 μM (amino acid transporter b0,+)[1]
In Vitro DL-Lysine (Lys) is a high affinity, basic amino acid substrate for amino acid transporter b0,+ with Km value ranging from 100-400 μM[1].
References [1]. Nguyen TV, et al. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange. Pharm Res. 2007 Feb;24(2):353-60.
Synonyms
Trans-1,4-cyclohexane dicarboxalic acid MonoMethyl ester
1,4-diamino-cyclohexane
EINECS 221-483-6
1,4-Diaminocyclohexane
TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL
cyclohexane-1,4-diamine
trans-cyclohexane-1,4-dicarboxylic acid monomethyl ester
TRANS-4-CARBOMETHOXYCYCLOHEXANE-1-CARBOXYLIC ACID
Cis or trans or mixture-1,4-diaminecyclohexane
MFCD00035862
trans-1,4-Cyclohexandicarbonsaeure-monomethylester
Methyl trans-4-carboxycyclohexane-1-carboxylate
trans-Cyclohexan-1,4-dicarbonsaeure-monomethylester
Product Description
Introduction: 1,4-Diaminocyclohexane, also known as 1,4-DACH, is a significant chemical compound with diverse applications in the chemical industry. This product introduction aims to provide an overview of 1,4-Diaminocyclohexane, covering its raw materials, production process, market trends, and the current status of amino acids in the industry.

Raw Materials: 1,4-Diaminocyclohexane is synthesized from cyclohexane through a series of chemical reactions. Cyclohexane serves as the primary raw material for the production of 1,4-Diaminocyclohexane.

Production Process:
The production process of 1,4-Diaminocyclohexane involves the following steps:
Step 1: Hydrogenation of cyclohexane - Cyclohexane undergoes hydrogenation in the presence of suitable catalysts and reaction conditions to convert it into 1,4-diaminocyclohexane.

Step 2: Purification and refinement - The resulting 1,4-diaminocyclohexane is purified and refined using techniques such as distillation, crystallization, and filtration to achieve the desired level of purity.

Market Trends: The market demand for 1,4-Diaminocyclohexane has been steadily increasing due to its diverse applications across various industries. Here are some key market trends: Polymer Industry: 1,4-Diaminocyclohexane is widely used in the production of polyamides, such as nylon. It serves as a key building block in the synthesis of various nylon resins, including nylon 6, nylon 66, and nylon 610. These polyamides find applications in automotive parts, electrical and electronic components, fibers, films, and other industrial applications.

Pharmaceuticals: 1,4-Diaminocyclohexane is utilized in the pharmaceutical industry. It is used as an intermediate in the synthesis of pharmaceutical compounds, including drugs targeting cardiovascular diseases, anti-cancer drugs, and medications for neurological disorders.

Current Status of Amino Acids: While 1,4-Diaminocyclohexane is not an amino acid, it is an important chemical compound used in various applications. Amino acids, on the other hand, play a crucial role in various sectors, including pharmaceuticals, food additives, animal nutrition, and agriculture. They are essential building blocks for proteins and have diverse functions in the human body.

Conclusion: 1,4-Diaminocyclohexane, derived from cyclohexane, holds significant value in the chemical industry. Its production involves the hydrogenation of cyclohexane, followed by purification and refinement. The market demand for 1,4-Diaminocyclohexane is driven by its applications in the polymer industry, particularly in the production of polyamides, as well as its usage as an intermediate in the pharmaceutical industry. Amino acids, although not directly related to 1,4-Diaminocyclohexane, continue to play a vital role in various industries and contribute to the advancement of chemical applications.

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